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Tbio
CRISPLD1
Cysteine-rich secretory protein LCCL domain-containing 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262207
  • ENSP00000262207
  • ENSG00000121005
  • ENST00000517786
  • ENSP00000429746

Symbol
  • CRISP10
  • LCRISP1
  • CRISP10
  • LCRISP1
  • CRISP-10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.92
microRNA
0.83
PubMedID
0.72
protein domain
0.58
cell line
0.54


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.93   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.93   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
SNRPF
Tbio
Novelty:  0.17624854
Score:  0.707
Data Source:  STRINGDB
KPTN
Tbio
Novelty:  0.06841936
Score:  0.677
Data Source:  STRINGDB
TMEM68
Tdark
Novelty:  0.61508475
Score:  0.642
Data Source:  STRINGDB
JPH1
Tbio
Novelty:  0.00931679
Score:  0.641
Data Source:  STRINGDB
GDAP1
Tbio
Novelty:  0.00682376
Score:  0.633
Data Source:  STRINGDB
ZNF287
Tdark
Family:  TF
Novelty:  1.01445884
Score:  0.598
Data Source:  STRINGDB
WDR38
Tdark
Novelty:  2.80851064
Score:  0.551
Data Source:  STRINGDB
SPAG8
Tbio
Novelty:  0.06962141
Score:  0.54
Data Source:  STRINGDB
CSNK1G2
Tchem
Family:  Kinase
Novelty:  0.17930147
Score:  0.535
Data Source:  STRINGDB
KIAA1324L
Tdark
Novelty:  0.49604915
Score:  0.533
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aortic measurement
3
1
3
23.7
BMI-adjusted waist circumference
1
2
2
17.6
appendicular lean mass
1
1
1
7.6
optic cup area measurement
1
1
1
6.8
BMI-adjusted hip circumference
2
1
2
4.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aortic measurement
3
23.7
BMI-adjusted waist circumference
2
17.6
appendicular lean mass
1
7.6
optic cup area measurement
1
6.8
BMI-adjusted hip circumference
2
4.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cysteine rich secretory protein LCCL domain containing 1
VGNC:6560
464240
Macaque
cysteine rich secretory protein LCCL domain containing 1
697491
Mouse
MGI:1934666
83691
Rat
RGD:1564813
316482
Dog
cysteine rich secretory protein LCCL domain containing 1
VGNC:39617
487004
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cysteine rich secretory protein LCCL domain containing 1
Macaque
cysteine rich secretory protein LCCL domain containing 1
Mouse
Rat
Dog
cysteine rich secretory protein LCCL domain containing 1
Publication Statistics
PubMed Score 12.93
PubMed score by year
PubTator Score 1.62
PubTator score by year
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Related Publications
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PMID
Year
Title