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Tbio
CRIP2
Cysteine-rich protein 2

Protein Summary
Description
This gene encodes a putative transcription factor with two LIM zinc-binding domains. The encoded protein may participate in the differentiation of smooth muscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329146
  • ENSP00000328521
  • ENSG00000182809
  • ENST00000483017
  • ENSP00000426119

Symbol
  • CRP2
  • CRIP
  • CRP2
  • ESP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.9
transcription factor perturbation
0.88
gene perturbation
0.76
transcription factor
0.75
tissue sample
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.33   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 195   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.33   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 195   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
ACOT6
Tdark
Family:  Enzyme
Novelty:  1.12818537
p_int:  0.992890916
p_ni:  0.002505739
p_wrong:  0.004603345
Score:  0.485
Data Source:  BioPlex,STRINGDB
SARNP
Tbio
Novelty:  0.00987312
p_int:  0.848270105
p_ni:  0.000316556
p_wrong:  0.151413339
Score:  0.213
Data Source:  BioPlex,STRINGDB
AEN
Tbio
Family:  Enzyme
Novelty:  0.04318322
p_int:  0.779468296
p_ni:  0.020364082
p_wrong:  0.200167623
Score:  0.416
Data Source:  BioPlex,STRINGDB
GLIPR2
Tbio
Novelty:  0.04546295
Score:  0.672
Data Source:  STRINGDB
HMG20B
Tbio
Family:  TF
Novelty:  0.05983143
Score:  0.664
Data Source:  STRINGDB
PRKG1
Tchem
Family:  Kinase
Novelty:  0.0014943
Score:  0.66
Data Source:  STRINGDB
KANK3
Tdark
Novelty:  0.35969246
Score:  0.565
Data Source:  STRINGDB
BCAR1
Tbio
Novelty:  0.00329214
Score:  0.557
Data Source:  STRINGDB
TMEM121
Tdark
Novelty:  0.18541234
Score:  0.549
Data Source:  STRINGDB
SRF
Tbio
Family:  TF
Novelty:  0.00088839
Score:  0.523
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
43
16
57
95.5
serum non-albumin protein measurement
1
4
4
88.8
heel bone mineral density
2
2
2
76.3
calcium measurement
3
3
3
73.7
serum albumin measurement
2
2
2
72.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
57
95.5
serum non-albumin protein measurement
4
88.8
heel bone mineral density
2
76.3
calcium measurement
3
73.7
serum albumin measurement
2
72.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
cysteine rich protein 2
710186
Mouse
MGI:1915587
68337
Rat
RGD:1302959
338401
Dog
cysteine rich protein 2
VGNC:39613
612710
Anole lizard
cysteine rich protein 2
100555726
Species
Name
OMA
EggNOG
Inparanoid
Macaque
cysteine rich protein 2
Mouse
Rat
Dog
cysteine rich protein 2
Anole lizard
cysteine rich protein 2
Publication Statistics
PubMed Score 68.33
PubMed score by year
PubTator Score 112.76
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title