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Tchem
CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

Protein Summary
Description
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371486
  • ENSP00000360541
  • ENSG00000157184

Symbol
  • CPT1
  • CPT1
  • IIAE4
  • CPTASE
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
metabolite
1
phenotype
0.77
cellular component
0.72
interacting protein
0.72
kinase perturbation
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 361.86   (req: < 5)
Gene RIFs: 48   (req: <= 3)
Antibodies: 454   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 361.86   (req: >= 5)
Gene RIFs: 48   (req: > 3)
Antibodies: 454   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 35
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0