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Tdark
CPSF4L
Putative cleavage and polyadenylation specificity factor subunit 4-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000344935
  • ENSP00000343900
  • ENSG00000187959
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.9
PubMedID
0.57
virus perturbation
0.55
transcription factor binding site profile
0.54
tissue
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.28   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 77   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.28   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
CCNG1
Tbio
Novelty:  0.00838635
p_int:  0.999991261
p_ni:  7.2e-8
p_wrong:  0.000008667
Score:  0.218
Data Source:  BioPlex,STRINGDB
WDR33
Tbio
Novelty:  0.09221439
p_int:  0.999963858
p_ni:  0.000036142
Score:  0.858
Data Source:  BioPlex,STRINGDB
BANP
Tbio
Novelty:  0.02145545
p_int:  0.997940961
p_ni:  0.00205901
p_wrong:  2.9e-8
Score:  0.222
Data Source:  BioPlex,STRINGDB
CCNH
Tbio
Novelty:  0.00693072
p_int:  0.984199103
p_ni:  0.015745044
p_wrong:  0.000055853
Score:  0.265
Data Source:  BioPlex,STRINGDB
FIP1L1
Tbio
Novelty:  0.00520044
p_int:  0.926602137
p_ni:  0.073397863
Score:  0.957
Data Source:  BioPlex,STRINGDB
AP2A2
Tbio
Novelty:  0.08851191
p_int:  0.894896418
p_ni:  0.105103582
Score:  0.18
Data Source:  BioPlex,STRINGDB
CPSF3
Tchem
Novelty:  0.01880576
p_int:  0.85597115
p_ni:  0.14402885
Score:  0.891
Data Source:  BioPlex,STRINGDB
CPSF2
Tbio
Novelty:  0.0510853
Score:  0.915
Data Source:  STRINGDB
NUDT21
Tbio
Novelty:  0.02174736
Score:  0.839
Data Source:  STRINGDB
CSTF3
Tbio
Novelty:  0.05260909
Score:  0.829
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
2
3
79.2
mean reticulocyte volume
1
1
1
74.6
mean corpuscular volume
1
1
1
71.9
mean corpuscular hemoglobin concentration
1
1
1
64.9
reticulocyte count
2
2
2
57.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
3
79.2
mean reticulocyte volume
1
74.6
mean corpuscular volume
1
71.9
mean corpuscular hemoglobin concentration
1
64.9
reticulocyte count
2
57.6
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cleavage and polyadenylation specific factor 4 like
VGNC:12055
744631
Macaque
cleavage and polyadenylation specific factor 4 like [Source:HGNC Symbol;Acc:HGNC:33632]
Mouse
MGI:1277182
52670
Horse
cleavage and polyadenylation specific factor 4 like
VGNC:51474
100061214
Opossum
cleavage and polyadenylation specific factor 4 like [Source:HGNC Symbol;Acc:HGNC:33632]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cleavage and polyadenylation specific factor 4 like
Macaque
cleavage and polyadenylation specific factor 4 like [Source:HGNC Symbol;Acc:HGNC:33632]
Mouse
Horse
cleavage and polyadenylation specific factor 4 like
Opossum
cleavage and polyadenylation specific factor 4 like [Source:HGNC Symbol;Acc:HGNC:33632]
Publication Statistics
PubMed Score 0.28
PubMed score by year
PubTator Score 0.08
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title