Protein Summary
Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003). Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. More variants may exist, but their full-length natures could not be determined. [provided by RefSeq, Sep 2015]
- ENST00000244751
- ENSP00000244751
- ENSG00000124772
- ENST00000393189
- ENSP00000376885
- KIAA1599
- CPN5
- COPN5
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 0.69 | ||
virus perturbation | 0.68 | ||
kinase perturbation | 0.6 | ||
cell line | 0.55 | ||
transcription factor binding site profile | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.35 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 103 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.35 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 103 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (46)
RAD54B
Novelty: 0.02431597
p_int: 0.999999998
p_ni: 2e-9
Score: 0.187
Data Source: BioPlex,STRINGDB
NCK1
Novelty: 0.00352084
p_int: 0.999998392
p_ni: 0.000001608
Score: 0.406
Data Source: BioPlex,STRINGDB
RABEP2
Family: Enzyme
Novelty: 0.18180682
p_int: 0.999995409
p_ni: 0.000004591
Score: 0.222
Data Source: BioPlex,STRINGDB
UTRN
Novelty: 0.0018541
p_int: 0.999863662
p_ni: 0.000136338
Score: 0.156
Data Source: BioPlex,STRINGDB
SNTB2
Novelty: 0.05469501
p_int: 0.999653775
p_ni: 0.000346224
p_wrong: 1e-9
Data Source: BioPlex
MBNL3
Novelty: 0.0492081
p_int: 0.999582295
p_ni: 0.000374283
p_wrong: 0.000043422
Score: 0.187
Data Source: BioPlex,STRINGDB
DTNB
Novelty: 0.0586565
p_int: 0.998669054
p_ni: 0.001330929
p_wrong: 1.7e-8
Data Source: BioPlex
GATAD2B
Family: TF
Novelty: 0.056775
p_int: 0.997683642
p_ni: 0.002316358
Score: 0.224
Data Source: BioPlex,STRINGDB
NCK2
Novelty: 0.02220251
p_int: 0.987902846
p_ni: 0.012093711
p_wrong: 0.000003442
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (1)
Components (4)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (28)
Items per page:
1 – 5 of 28
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
electrocardiography | 2 | 2 | 16 | 6.5 | 77.7 | ||||
QRS duration | 2 | 2 | 1 | 6.5 | 77.4 | ||||
3 | 2 | 1 | 1.3 | 74.6 | |||||
neutrophil count | 2 | 2 | 2 | 73.4 | |||||
2 | 2 | 0 | 1.1 | 71.1 | |||||
Items per page:
1 – 5 of 28
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
electrocardiography | 16 | 6.5 | 77.7 | ||||
QRS duration | 1 | 6.5 | 77.4 | ||||
1 | 1.3 | 74.6 | |||||
neutrophil count | 2 | 73.4 | |||||
0 | 1.1 | 71.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | copine 5 | VGNC:7168 | 462651 | |||||
Macaque | copine 5 | 719255 | ||||||
Mouse | MGI:2385908 | 240058 | ||||||
Rat | RGD:1308021 | 309650 | ||||||
Dog | copine 5 | VGNC:39564 | 481768 | |||||
Publication Statistics
PubMed Score 11.35
PubMed score by year
PubTator Score 4.09
PubTator score by year
Related Publications
Text Mined References (14)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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