CPA5
Carboxypeptidase A5
Protein Summary
Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008]
- ENST00000393213
- ENSP00000376907
- ENSG00000158525
- ENST00000431780
- ENSP00000393045
- ENST00000461828
- ENSP00000418183
- ENST00000466363
- ENSP00000419025
- ENST00000474905
- ENSP00000417314
- ENST00000485477
- ENSP00000420237
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 0.71 | ||
molecular function | 0.56 | ||
cell type or tissue | 0.49 | ||
tissue | 0.49 | ||
metabolite | 0.45 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 25.54 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 84 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 25.54 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 84 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0