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Tbio
COX6B2
Cytochrome c oxidase subunit 6B2

Protein Summary
Description
Connects the two COX monomers into the physiological dimeric form.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326529
  • ENSP00000320672
  • ENSG00000160471
  • ENST00000588572
  • ENSP00000467959
  • ENST00000589467
  • ENSP00000476768
  • ENST00000590900
  • ENSP00000467128
  • ENST00000593184
  • ENSP00000467266

Symbol
  • CT59
  • COXVIB2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.72
tissue sample
0.71
molecular function
0.67
cellular component
0.56
transcription factor
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.81   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.81   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (114)
COX6A2
Tbio
Family:  Enzyme
Novelty:  0.05368739
Score:  0.983
Data Source:  STRINGDB
COX5A
Tbio
Family:  Enzyme
Novelty:  0.02110193
Score:  0.98
Data Source:  STRINGDB
COX6C
Tbio
Family:  Enzyme
Novelty:  0.04365165
Score:  0.976
Data Source:  STRINGDB
COX5B
Tbio
Family:  Enzyme
Novelty:  0.01729026
Score:  0.966
Data Source:  STRINGDB
COX6A1
Tbio
Family:  Enzyme
Novelty:  0.05543187
Score:  0.963
Data Source:  STRINGDB
COX7C
Tbio
Family:  Enzyme
Novelty:  0.05516787
Score:  0.962
Data Source:  STRINGDB
UQCRQ
Tbio
Novelty:  0.04392627
Score:  0.952
Data Source:  STRINGDB
UQCRFS1
Tbio
Novelty:  0.00341256
Score:  0.942
Data Source:  STRINGDB
COX4I2
Tbio
Family:  Enzyme
Novelty:  0.00965049
Score:  0.932
Data Source:  STRINGDB
COX4I1
Tbio
Family:  Enzyme
Novelty:  0.00208873
Score:  0.931
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (10)
Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
Non-alcoholic fatty liver disease (NAFLD)
KEGG
Alzheimer disease
KEGG
Huntington disease
KEGG
Thermogenesis
KEGG
Cardiac muscle contraction
Name
Explore in Pharos
Explore in Source
Non-alcoholic fatty liver disease (NAFLD)
Alzheimer disease
Huntington disease
Thermogenesis
Cardiac muscle contraction
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menopause
4
2
4
98.1
appendicular lean mass
3
1
3
85.9
estradiol measurement
4
1
3
8.8
78.1
2
1
0
1.3
73.5
mean corpuscular hemoglobin concentration
1
1
1
51
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menopause
4
98.1
appendicular lean mass
3
85.9
estradiol measurement
3
8.8
78.1
0
1.3
73.5
mean corpuscular hemoglobin concentration
1
51
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cytochrome c oxidase subunit 6B2
VGNC:10982
469014
Mouse
MGI:3044182
333182
Rat
RGD:1591896
654441
Cow
cytochrome c oxidase subunit 6B2
VGNC:27638
503554
Opossum
cytochrome c oxidase subunit 6B2-like
100020481
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cytochrome c oxidase subunit 6B2
Mouse
Rat
Cow
cytochrome c oxidase subunit 6B2
Opossum
cytochrome c oxidase subunit 6B2-like
Publication Statistics
PubMed Score 8.81
PubMed score by year
PubTator Score 0.61
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title