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Tdark
CORO6
Coronin-6

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.33   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 121   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.33   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 121   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
CORO1A
Tbio
Novelty:  0.00898925
p_int:  1
Score:  0.667
Data Source:  BioPlex,STRINGDB
CORO1C
Tbio
Novelty:  0.02068813
p_int:  0.999999721
p_ni:  2.79e-7
Score:  0.824
Data Source:  BioPlex,STRINGDB
UACA
Tbio
Novelty:  0.05853699
p_int:  0.999998779
p_ni:  0.00000122
p_wrong:  1e-9
Score:  0.22
Data Source:  BioPlex,STRINGDB
TRIOBP
Tbio
Novelty:  0.04145641
p_int:  0.999995265
p_ni:  0.000004733
p_wrong:  1e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
TACC3
Tbio
Novelty:  0.00708723
p_int:  0.999788103
p_ni:  0.000211897
Data Source:  BioPlex
NBR1
Tbio
Novelty:  0.00893066
p_int:  0.998719624
p_ni:  0.001280288
p_wrong:  8.9e-8
Score:  0.201
Data Source:  BioPlex,STRINGDB
CORO1B
Tbio
Novelty:  0.05912813
p_int:  0.996170103
p_ni:  0.003829897
Score:  0.824
Data Source:  BioPlex,STRINGDB
POC1A
Tbio
Novelty:  0.03897985
p_int:  0.995633523
p_ni:  0.004366477
Data Source:  BioPlex
KAT14
Tbio
Novelty:  0.17168043
p_int:  0.992981285
p_ni:  0.007018715
Data Source:  BioPlex
C9orf16
Tdark
Novelty:  1.20658855
p_int:  0.974021881
p_ni:  0.000102559
p_wrong:  0.025875559
Score:  0.189
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
87.7
platelet count
1
1
1
85.9
heel bone mineral density
2
1
2
82.5
lymphocyte count
2
2
2
82.4
BMI-adjusted waist-hip ratio
2
2
3
74
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
87.7
platelet count
1
85.9
heel bone mineral density
2
82.5
lymphocyte count
2
82.4
BMI-adjusted waist-hip ratio
3
74
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coronin 6
VGNC:9246
736071
Mouse
MGI:2183448
216961
Rat
RGD:708560
245982
Dog
coronin 6
VGNC:39531
491182
Horse
coronin 6
VGNC:16795
100059746
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coronin 6
Mouse
Rat
Dog
coronin 6
Horse
coronin 6
Publication Statistics
PubMed Score 3.33
PubMed score by year
PubTator Score 0.96
PubTator score by year
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Related Publications
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PMID
Year
Title