You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
CORO2B
Coronin-2B

Protein Summary
Description
May play a role in the reorganization of neuronal actin structure.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261861
  • ENSP00000261861
  • ENSG00000103647
  • ENST00000540068
  • ENSP00000446250
  • ENST00000543950
  • ENSP00000443819
  • ENST00000566799
  • ENSP00000454783

Symbol
  • KIAA0925
  • CLIPINC
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
gene perturbation
0.82
transcription factor
0.73
microRNA
0.65
transcription factor binding site profile
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.55   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.55   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (53)
CORO2A
Tbio
Novelty:  0.03292199
p_int:  0.999999998
p_ni:  2e-9
Score:  0.324
Data Source:  BioPlex,STRINGDB
PRKG1
Tchem
Family:  Kinase
Novelty:  0.0014943
p_int:  0.999485994
p_ni:  0.000514005
p_wrong:  1e-9
Score:  0.397
Data Source:  BioPlex,STRINGDB
SHC1
Tchem
Novelty:  0.00083615
p_int:  0.999413613
p_ni:  0.000586343
p_wrong:  4.4e-8
Score:  0.236
Data Source:  BioPlex,STRINGDB
ARHGEF25
Tbio
Novelty:  0.02782136
p_int:  0.94887039
p_ni:  0.021891424
p_wrong:  0.029238186
Score:  0.502
Data Source:  BioPlex,STRINGDB
ITGA11
Tbio
Novelty:  0.02501472
Score:  0.805
Data Source:  STRINGDB
TLE3
Tbio
Novelty:  0.02641884
Score:  0.8
Data Source:  STRINGDB
VCL
Tbio
Novelty:  0.00043107
Score:  0.718
Data Source:  STRINGDB
KIF23
Tbio
Novelty:  0.00719651
Score:  0.68
Data Source:  STRINGDB
ARHGEF2
Tbio
Novelty:  0.01494954
Score:  0.665
Data Source:  STRINGDB
PXYLP1
Tbio
Family:  Enzyme
Novelty:  0.04672634
Score:  0.61
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.6
10.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.6
10.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coronin 2B
VGNC:6600
453538
Macaque
coronin 2B
694229
Mouse
MGI:2444283
235431
Rat
RGD:1561953
300768
Dog
coronin 2B
VGNC:39530
487618
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coronin 2B
Macaque
coronin 2B
Mouse
Rat
Dog
coronin 2B
Publication Statistics
PubMed Score 4.55
PubMed score by year
PubTator Score 1.17
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title