COL10A1
Collagen alpha-1(X) chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.7 | ||
small molecule perturbation | 0.59 | ||
phenotype | 0.54 | ||
biological term | 0.53 | ||
cell line | 0.52 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Assembly of collagen fibrils and other multimeric structures | ||||
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen chain trimerization | ||||
Reactome | Collagen formation | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Assembly of collagen fibrils and other multimeric structures | ||||
Collagen biosynthesis and modifying enzymes | ||||
Collagen chain trimerization | ||||
Collagen formation | ||||
Extracellular matrix organization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 3 | 3 | 3 | 83.1 | |||||
total cholesterol measurement | 3 | 3 | 3 | 69.4 | |||||
refractive error measurement | 2 | 2 | 1 | 6.5 | 64.2 | ||||
Myopia | 2 | 1 | 0 | 3.8 | 58.4 | ||||
age at onset | 1 | 1 | 0 | 6.5 | 46.1 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 3 | 83.1 | |||||
total cholesterol measurement | 3 | 69.4 | |||||
refractive error measurement | 1 | 6.5 | 64.2 | ||||
Myopia | 0 | 3.8 | 58.4 | ||||
age at onset | 0 | 6.5 | 46.1 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | collagen type X alpha 1 chain | VGNC:10661 | 742603 | |||||
Mouse | MGI:88445 | 12813 | ||||||
Rat | RGD:2371 | 25681 | ||||||
Dog | collagen type X alpha 1 chain | VGNC:39455 | 100856711 | |||||
Horse | collagen type X alpha 1 chain | VGNC:16720 | 100066959 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | collagen type X alpha 1 chain | |||||
Mouse | ||||||
Rat | ||||||
Dog | collagen type X alpha 1 chain | |||||
Horse | collagen type X alpha 1 chain | |||||
PMID | Year | Title |
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