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Tbio
CNTNAP3
Contactin-associated protein-like 3

Protein Summary
Description
The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297668
  • ENSP00000297668
  • ENSG00000106714

Symbol
  • CASPR3
  • KIAA1714
  • CASPR3
  • CNTNAP3A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
tissue sample
0.68
microRNA
0.62
tissue
0.56
cell line
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.41   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.41   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (80)
CNTNAP3B
Tdark
Novelty:  0.25889644
p_int:  0.999999998
p_ni:  2e-9
Data Source:  BioPlex
SCGB1D1
Tbio
Novelty:  0.04199997
p_int:  0.999717413
p_ni:  0.000282587
Data Source:  BioPlex
SCGB1D4
Tdark
Novelty:  0.15597658
p_int:  0.999705931
p_ni:  0.000294069
Data Source:  BioPlex
TAZ
Tbio
Novelty:  0.00372301
p_int:  0.999510424
p_ni:  0.000489575
Data Source:  BioPlex
ERLEC1
Tbio
Novelty:  0.01243855
p_int:  0.999220728
p_ni:  0.000779272
Score:  0.167
Data Source:  BioPlex,STRINGDB
SCGB2A2
Tbio
Novelty:  0.01594053
p_int:  0.998979605
p_ni:  0.001020395
Data Source:  BioPlex
HLA-E
Tbio
Novelty:  0.00216583
p_int:  0.998866598
p_ni:  0.001133402
Data Source:  BioPlex
PTCH1
Tbio
Novelty:  0.00077635
p_int:  0.998786255
p_ni:  0.001213745
Data Source:  BioPlex
HYOU1
Tbio
Novelty:  0.00833649
p_int:  0.998329937
p_ni:  0.001670063
Data Source:  BioPlex
SLAMF1
Tbio
Novelty:  0.00112892
p_int:  0.998283102
p_ni:  0.001716897
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
contactin associated protein-like 3
464928
Species
Name
OMA
EggNOG
Inparanoid
Chimp
contactin associated protein-like 3
Publication Statistics
PubMed Score 5.41
PubMed score by year
PubTator Score 5.05
PubTator score by year
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Related Publications
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PMID
Year
Title