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Tbio
CNNM3
Metal transporter CNNM3

Protein Summary
Description
Probable metal transporter.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305510
  • ENSP00000305449
  • ENSG00000168763
  • ENST00000377060
  • ENSP00000366260

Symbol
  • ACDP3
  • ACDP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor binding site profile
0.74
microRNA
0.69
tissue sample
0.66
tissue
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.24   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 183   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.24   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 183   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
PTP4A1
Tchem
Family:  Enzyme
Novelty:  0.02863007
p_int:  0.964217049
p_ni:  0.035782951
Score:  0.914
Data Source:  BioPlex,STRINGDB
PTP4A2
Tchem
Family:  Enzyme
Novelty:  0.0083639
Score:  0.988
Data Source:  STRINGDB
PTP4A3
Tchem
Family:  Enzyme
Novelty:  0.01185448
Score:  0.972
Data Source:  STRINGDB
HPSE2
Tbio
Family:  Enzyme
Novelty:  0.00583615
Score:  0.757
Data Source:  STRINGDB
CRABP2
Tchem
Novelty:  0.0050363
Score:  0.72
Data Source:  STRINGDB
FAHD2B
Tdark
Family:  Enzyme
Novelty:  1.47557507
Score:  0.659
Data Source:  STRINGDB
CCNQ
Tdark
Novelty:  0.08298637
Score:  0.655
Data Source:  STRINGDB
FAM178B
Tdark
Novelty:  3.72734051
Score:  0.64
Data Source:  STRINGDB
FNDC3A
Tbio
Novelty:  0.04721453
Score:  0.627
Data Source:  STRINGDB
ANKRD39
Tdark
Novelty:  8.68843298
Score:  0.596
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
calcium measurement
3
6
6
94.9
blood protein measurement
1
1
1
64.5
mathematical ability
3
1
3
56.7
birth weight
1
1
1
41.3
body height
1
1
1
36.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
calcium measurement
6
94.9
blood protein measurement
1
64.5
mathematical ability
3
56.7
birth weight
1
41.3
body height
1
36.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cyclin and CBS domain divalent metal cation transport mediator 3
VGNC:201
740778
Macaque
cyclin and CBS domain divalent metal cation transport mediator 4 precursor [Source:RefSeq peptide;Acc:NP_001343488]
Mouse
MGI:2151055
94218
Rat
RGD:1307926
301345
Dog
cyclin and CBS domain divalent metal cation transport mediator 3
VGNC:39408
481345
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cyclin and CBS domain divalent metal cation transport mediator 3
Macaque
cyclin and CBS domain divalent metal cation transport mediator 4 precursor [Source:RefSeq peptide;Acc:NP_001343488]
Mouse
Rat
Dog
cyclin and CBS domain divalent metal cation transport mediator 3
Publication Statistics
PubMed Score 10.24
PubMed score by year
PubTator Score 4.73
PubTator score by year
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Related Publications
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PMID
Year
Title