Protein Summary
Probable metal transporter. This gene encodes a member of the ancient conserved domain protein family. The encoded protein may bind copper. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
- ENST00000356713
- ENSP00000349147
- ENSG00000119946
- ACDP1
- ACDP1
- CLP-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.81 | ||
microRNA | 0.81 | ||
phenotype | 0.66 | ||
PubMedID | 0.62 | ||
small molecule perturbation | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.52 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 41 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.52 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 41 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (85)
PTP4A1
Family: Enzyme
Novelty: 0.02863007
p_int: 0.999999649
p_ni: 3.51e-7
Score: 0.791
Data Source: BioPlex,STRINGDB
PTP4A2
Family: Enzyme
Novelty: 0.0083639
p_int: 0.999999203
p_ni: 7.91e-7
p_wrong: 5e-9
Score: 0.789
Data Source: BioPlex,STRINGDB
BTNL8
Novelty: 0.40339869
p_int: 0.999515998
p_ni: 0.000483758
p_wrong: 2.44e-7
Score: 0.15
Data Source: BioPlex,STRINGDB
FCER1A
Novelty: 0.00362182
p_int: 0.999281826
p_ni: 0.000718172
p_wrong: 2e-9
Data Source: BioPlex
FDFT1
Family: Enzyme
Novelty: 0.00225882
p_int: 0.999022393
p_ni: 0.00097411
p_wrong: 0.000003497
Score: 0.174
Data Source: BioPlex,STRINGDB
ASIC4
Family: IC
Novelty: 0.02912816
p_int: 0.998714938
p_ni: 0.001285059
p_wrong: 3e-9
Data Source: BioPlex
PTCH1
Novelty: 0.00077635
p_int: 0.998419358
p_ni: 0.001580628
p_wrong: 1.3e-8
Score: 0.169
Data Source: BioPlex,STRINGDB
P01911
Novelty: 0.00240724
p_int: 0.997755524
p_ni: 0.002244459
p_wrong: 1.6e-8
Data Source: BioPlex
HFE
Novelty: 0.00042077
p_int: 0.996582265
p_ni: 0.00305691
p_wrong: 0.000360825
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (5)
Components (4)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Disease Associations ()
GWAS Traits (3)
Items per page:
1 – 3 of 3
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
aspartate aminotransferase measurement | 2 | 2 | 2 | 88.6 | |||||
monocyte percentage of leukocytes | 1 | 1 | 1 | 7.5 | |||||
platelet crit | 1 | 1 | 1 | 2.6 | |||||
Items per page:
1 – 3 of 3
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
aspartate aminotransferase measurement | 2 | 88.6 | |||||
monocyte percentage of leukocytes | 1 | 7.5 | |||||
platelet crit | 1 | 2.6 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | cyclin and CBS domain divalent metal cation transport mediator 1 | VGNC:12285 | 466178 | |||||
Mouse | MGI:1891366 | 83674 | ||||||
Rat | RGD:1308728 | 309387 | ||||||
Dog | cyclin and CBS domain divalent metal cation transport mediator 1 | VGNC:39406 | 486833 | |||||
Horse | cyclin and CBS domain divalent metal cation transport mediator 1 | VGNC:50661 | 100070574 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | cyclin and CBS domain divalent metal cation transport mediator 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | cyclin and CBS domain divalent metal cation transport mediator 1 | |||||
Horse | cyclin and CBS domain divalent metal cation transport mediator 1 | |||||
Publication Statistics
PubMed Score 8.52
PubMed score by year
PubTator Score 3.78
PubTator score by year
Related Publications
Text Mined References (10)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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