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Tbio
CMIP
C-Maf-inducing protein

Protein Summary
Description
Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor. This gene encodes a c-Maf inducing protein that plays a role in T-cell signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398040
  • ENSP00000381120
  • ENSG00000153815
  • ENST00000537098
  • ENSP00000446100
  • ENST00000539778
  • ENSP00000440401

Symbol
  • KIAA1694
  • TCMIP
  • TCMIP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
transcription factor perturbation
0.91
transcription factor binding site profile
0.84
transcription factor
0.82
disease perturbation
0.79


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 135.42   (req: < 5)
Gene RIFs: 19   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 135.42   (req: >= 5)
Gene RIFs: 19   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
C8A
Tbio
Novelty:  0.00429321
p_int:  0.986433649
p_ni:  0.013446662
p_wrong:  0.000119689
Data Source:  BioPlex
RILPL1
Tbio
Novelty:  0.04302386
p_int:  0.980620782
p_ni:  3.3e-8
p_wrong:  0.019379185
Data Source:  BioPlex
INPPL1
Tchem
Family:  Enzyme
Novelty:  0.00634126
p_int:  0.978813827
p_ni:  0.021186173
Data Source:  BioPlex
P2RY1
Tchem
Family:  GPCR
Novelty:  0.00203299
p_int:  0.914885122
p_ni:  2.13e-7
p_wrong:  0.085114666
Score:  0.517
Data Source:  BioPlex,STRINGDB
FLNA
Tbio
Novelty:  0.00156479
Score:  0.867
Data Source:  STRINGDB
ATP2C2
Tbio
Family:  Transporter
Novelty:  0.03299453
Score:  0.816
Data Source:  STRINGDB
KIAA0319
Tbio
Novelty:  0.01425914
Score:  0.751
Data Source:  STRINGDB
CNTNAP2
Tbio
Novelty:  0.00238905
Score:  0.696
Data Source:  STRINGDB
DCDC2
Tbio
Novelty:  0.00395729
Score:  0.688
Data Source:  STRINGDB
MAF
Tbio
Family:  TF
Novelty:  0.00040887
Score:  0.677
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
No disease associations found
GWAS Traits (43)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
7
24
30
98.8
waist-hip ratio
3
23
25
98.8
testosterone measurement
5
5
6
98.5
high density lipoprotein cholesterol measurement
12
3
20
97
heel bone mineral density
3
7
8
97
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
30
98.8
waist-hip ratio
25
98.8
testosterone measurement
6
98.5
high density lipoprotein cholesterol measurement
20
97
heel bone mineral density
8
97
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
c-Maf inducing protein
VGNC:9023
454388
Mouse
MGI:1921690
74440
Rat
RGD:1306101
292051
Dog
c-Maf inducing protein
VGNC:53321
100686020
Horse
c-Maf inducing protein
VGNC:51156
100069901
Species
Name
OMA
EggNOG
Inparanoid
Chimp
c-Maf inducing protein
Mouse
Rat
Dog
c-Maf inducing protein
Horse
c-Maf inducing protein
Publication Statistics
PubMed Score 135.42
PubMed score by year
PubTator Score 36.73
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title