Tbio CMC4 Cx9C motif-containing protein 4

Protein Summary

Description

This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009]

Uniprot Accession IDs

• P56277
• Q5HYP9

Gene Name

• CMC4

Ensembl ID

• ENST00000369479
• ENSP00000358491
• ENSG00000182712
• ENST00000369484
• ENSP00000358496

Symbol

• C6.1B
• MTCP1
• MTCP1NB
• p8
• C6.1B
• MTCP1
• MTCP1B
• MTCP1NB
• p8MTCP1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.87
cell type or tissue	0.8
histone modification site profile	0.73
tissue sample	0.67
gene perturbation	0.62

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.7   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 62   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.7   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0