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Tdark
CLPSL1
Colipase-like protein 1

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.07   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.07   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
TNFAIP1
Tbio
Novelty:  0.04006419
p_int:  0.996972596
p_ni:  0.002968478
p_wrong:  0.000058926
Score:  0.239
Data Source:  BioPlex,STRINGDB
SLC30A5
Tbio
Family:  Transporter
Novelty:  0.02432633
p_int:  0.989853136
p_ni:  0.01014582
p_wrong:  0.000001044
Score:  0.167
Data Source:  BioPlex,STRINGDB
ZYG11B
Tbio
Novelty:  0.14657862
p_int:  0.980375742
p_ni:  0.019624258
Score:  0.183
Data Source:  BioPlex,STRINGDB
ZER1
Tbio
Novelty:  0.02989698
p_int:  0.899133257
p_ni:  0.100866743
Score:  0.188
Data Source:  BioPlex,STRINGDB
NUDT15
Tbio
Family:  Enzyme
Novelty:  0.008497
p_int:  0.805069689
p_ni:  0.01981423
p_wrong:  0.175116081
Score:  0.269
Data Source:  BioPlex,STRINGDB
LRP5
Tbio
Novelty:  0.00089807
p_int:  0.770028799
p_ni:  0.229969071
p_wrong:  0.00000213
Score:  0.181
Data Source:  BioPlex,STRINGDB
PATE3
Tdark
Novelty:  0.64960844
Score:  0.589
Data Source:  STRINGDB
DEFB132
Tdark
Novelty:  0.43147041
Score:  0.575
Data Source:  STRINGDB
TMEM52
Tdark
Novelty:  0.78121918
Score:  0.554
Data Source:  STRINGDB
SLCO1B7
Tdark
Family:  Transporter
Novelty:  0.48557976
Score:  0.53
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
2
2
72.1
BMI-adjusted waist-hip ratio
1
2
2
69.1
reticulocyte measurement
2
1
2
68.8
mean reticulocyte volume
1
1
1
63.4
BMI-adjusted waist circumference
1
2
2
63
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
2
72.1
BMI-adjusted waist-hip ratio
2
69.1
reticulocyte measurement
2
68.8
mean reticulocyte volume
1
63.4
BMI-adjusted waist circumference
2
63
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
colipase like 1
VGNC:2673
747681
Macaque
colipase like 1
718918
Species
Name
OMA
EggNOG
Inparanoid
Chimp
colipase like 1
Macaque
colipase like 1
Publication Statistics
PubMed Score 3.07
PubMed score by year
PubTator Score 2.00
PubTator score by year
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Related Publications
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PMID
Year
Title