Protein Summary
- ENST00000298912
- ENSP00000298912
- ENSG00000165959
- KIAA1188
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.97 | ||
gene perturbation | 0.82 | ||
cell type or tissue | 0.8 | ||
trait | 0.75 | ||
histone modification site profile | 0.63 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.18 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 53 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.18 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 53 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (33)
UBL4B
Novelty: 0.56877836
p_int: 0.999950574
p_ni: 0.000047276
p_wrong: 0.00000215
Data Source: BioPlex
ADCY9
Family: Enzyme
Novelty: 0.00744116
p_int: 0.999757303
p_ni: 0.000242384
p_wrong: 3.12e-7
Data Source: BioPlex
CCSMST1
Novelty: 0.60610244
p_int: 0.999480869
p_ni: 5.57e-7
p_wrong: 0.000518574
Data Source: BioPlex
TCTEX1D2
Novelty: 0.15075459
p_int: 0.997577546
p_ni: 1.77e-7
p_wrong: 0.002422277
Score: 0.369
Data Source: BioPlex,STRINGDB
TAOK2
Family: Kinase
Novelty: 0.0232708
p_int: 0.996764891
p_ni: 0.003206012
p_wrong: 0.000029097
Data Source: BioPlex
UQCC1
Family: Enzyme
Novelty: 0.03937066
p_int: 0.966911126
p_ni: 0.033088874
Data Source: BioPlex
SUN2
Novelty: 0.01387591
p_int: 0.825991541
p_ni: 0.173993473
p_wrong: 0.000014986
Score: 0.171
Data Source: BioPlex,STRINGDB
RAB21
Family: Enzyme
Novelty: 0.03221825
p_int: 0.82020123
p_ni: 0.179730691
p_wrong: 0.000068078
Data Source: BioPlex
Nearest Tclin Targets
Pathways (4)
WikiPathways (4)
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
WikiPathways | Vitamin D Receptor Pathway | ||||
WikiPathways | Vitamin D Receptor Pathway | ||||
WikiPathways | Vitamin D Receptor Pathway | ||||
WikiPathways | Ras Signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Vitamin D Receptor Pathway | ||||
Vitamin D Receptor Pathway | ||||
Vitamin D Receptor Pathway | ||||
Ras Signaling | ||||
Viral Interactions (0)
Gene Ontology Terms (10)
Functions (1)
Components (4)
Processes (5)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 3 | 4 | 86 | |||||
sex hormone-binding globulin measurement | 2 | 1 | 2 | 42.3 | |||||
1 | 1 | 1 | 21.5 | ||||||
gut microbiome measurement | 1 | 1 | 0 | 5.5 | 15.8 | ||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 4 | 86 | |||||
sex hormone-binding globulin measurement | 2 | 42.3 | |||||
1 | 21.5 | ||||||
gut microbiome measurement | 0 | 5.5 | 15.8 | ||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | calmin | VGNC:13032 | 742863 | |||||
Macaque | calmin | 709910 | ||||||
Mouse | MGI:2136957 | 94040 | ||||||
Rat | RGD:1306741 | 299285 | ||||||
Dog | calmin | VGNC:39350 | 480427 | |||||
Publication Statistics
PubMed Score 15.18
PubMed score by year
PubTator Score 10.76
PubTator score by year
Related Publications
Text Mined References (12)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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