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Tdark
CLEC3A
C-type lectin domain family 3 member A

Protein Summary
Description
Promotes cell adhesion to laminin-332 and fibronectin.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000575655
  • ENSP00000460682
  • ENSG00000166509

Symbol
  • CLECSF1
  • CLECSF1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.67
protein domain
0.58
microRNA
0.57
cell line
0.55
disease
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.35   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.35   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (110)
RNASEH1
Tchem
Family:  Enzyme
Novelty:  0.01838314
p_int:  0.999998819
p_ni:  2.7e-8
p_wrong:  0.000001154
Score:  0.19
Data Source:  BioPlex,STRINGDB
PHF10
Tbio
Family:  Epigenetic
Novelty:  0.05941323
p_int:  0.999993971
p_ni:  0.000006029
Data Source:  BioPlex
YY1AP1
Tbio
Novelty:  0.06862573
p_int:  0.999945796
p_ni:  0.000054204
Score:  0.519
Data Source:  BioPlex,STRINGDB
ZNF430
Tdark
Family:  TF
Novelty:  3.98895047
p_int:  0.999803884
p_ni:  0.000196116
Score:  0.173
Data Source:  BioPlex,STRINGDB
CACTIN
Tbio
Novelty:  0.03222124
p_int:  0.99976196
p_ni:  0.000238036
p_wrong:  4e-9
Score:  0.15
Data Source:  BioPlex,STRINGDB
RBM23
Tbio
Novelty:  0.03769792
p_int:  0.999735231
p_ni:  0.000264764
p_wrong:  4e-9
Data Source:  BioPlex
KBTBD7
Tdark
Novelty:  0.4947466
p_int:  0.999443335
p_ni:  0.000556665
Data Source:  BioPlex
CTNNBL1
Tbio
Novelty:  0.0189038
p_int:  0.999133728
p_ni:  0.000591421
p_wrong:  0.000274851
Score:  0.499
Data Source:  BioPlex,STRINGDB
LSM14B
Tdark
Novelty:  0.31832554
p_int:  0.999029893
p_ni:  0.000970107
Data Source:  BioPlex
C1QBP
Tbio
Novelty:  0.00532825
p_int:  0.997856523
p_ni:  0.002143477
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
57.8
eosinophil count
2
1
2
46.1
vital capacity
1
1
0
16.3
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
57.8
eosinophil count
2
46.1
vital capacity
0
16.3
24.5
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2685642
403395
Rat
RGD:1306295
365009
Dog
C-type lectin domain family 3 member A
VGNC:39331
610142
Horse
C-type lectin domain family 3 member A
VGNC:16603
100055505
Cow
C-type lectin domain family 3 member A
VGNC:27428
282415
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
C-type lectin domain family 3 member A
Horse
C-type lectin domain family 3 member A
Cow
C-type lectin domain family 3 member A
Publication Statistics
PubMed Score 7.35
PubMed score by year
PubTator Score 2.29
PubTator score by year
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Related Publications
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PMID
Year
Title