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Tbio
CLDND1
Claudin domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341181
  • ENSP00000340247
  • ENSG00000080822
  • ENST00000394180
  • ENSP00000377734
  • ENST00000394185
  • ENSP00000377739
  • ENST00000503004
  • ENSP00000421226
  • ENST00000510545
  • ENSP00000423590
  • ENST00000511081
  • ENSP00000424669
  • ENST00000513287
  • ENSP00000426869

Symbol
  • C3orf4
  • Z38
  • C3orf4
  • GENX-3745
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.68
tissue
0.6
transcription factor binding site profile
0.59
small molecule perturbation
0.56
kinase perturbation
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.27   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 140   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.27   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 140   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (28)
ZDHHC5
Tbio
Family:  Enzyme
Novelty:  0.05205767
p_int:  0.999999979
p_ni:  6e-9
p_wrong:  1.5e-8
Score:  0.812
Data Source:  BioPlex,STRINGDB
ZDHHC8
Tbio
Family:  Enzyme
Novelty:  0.03434357
p_int:  0.999999974
p_wrong:  2.6e-8
Score:  0.269
Data Source:  BioPlex,STRINGDB
GOLGA7
Tbio
Novelty:  0.17108842
p_int:  0.999999715
p_ni:  2.84e-7
p_wrong:  1e-9
Score:  0.784
Data Source:  BioPlex,STRINGDB
LYPD3
Tbio
Novelty:  0.03248533
p_int:  0.99995127
p_ni:  0.000048529
p_wrong:  2.01e-7
Data Source:  BioPlex
HAVCR2
Tbio
Novelty:  0.00155885
p_int:  0.99993773
p_ni:  0.00006227
Data Source:  BioPlex
MAN1A2
Tbio
Family:  Enzyme
Novelty:  0.15637608
p_int:  0.999882475
p_ni:  0.000117525
Score:  0.209
Data Source:  BioPlex,STRINGDB
TMEFF1
Tbio
Novelty:  0.11856207
p_int:  0.999636509
p_ni:  0.000080331
p_wrong:  0.000283161
Score:  0.546
Data Source:  BioPlex,STRINGDB
MAN1A1
Tbio
Family:  Enzyme
Novelty:  0.00645679
p_int:  0.999620231
p_ni:  0.000301609
p_wrong:  0.000078161
Score:  0.209
Data Source:  BioPlex,STRINGDB
GYPA
Tbio
Novelty:  0.00067203
p_int:  0.999373195
p_ni:  0.000542726
p_wrong:  0.000084079
Score:  0.392
Data Source:  BioPlex,STRINGDB
SLC44A5
Tdark
Family:  Transporter
Novelty:  0.15262166
p_int:  0.999364504
p_ni:  0.000313268
p_wrong:  0.000322228
Score:  0.167
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
claudin domain containing 1
698472
Mouse
MGI:2447860
224250
Rat
RGD:1359273
288182
Dog
claudin domain containing 1
VGNC:39324
478534
Horse
claudin domain containing 1
VGNC:16598
100072425
Species
Name
OMA
EggNOG
Inparanoid
Macaque
claudin domain containing 1
Mouse
Rat
Dog
claudin domain containing 1
Horse
claudin domain containing 1
Publication Statistics
PubMed Score 17.27
PubMed score by year
PubTator Score 3.62
PubTator score by year
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Related Publications
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PMID
Year
Title