CKM
Creatine kinase M-type
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.91 | ||
molecular function | 0.9 | ||
disease | 0.79 | ||
disease perturbation | 0.74 | ||
protein domain | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Creatine metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Creatine metabolism | ||||
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
creatine kinase measurement | 4 | 4 | 7 | 98.4 | |||||
mean platelet volume | 4 | 3 | 5 | 98 | |||||
platelet count | 3 | 6 | 5 | 2.6 | 97.9 | ||||
leukocyte count | 2 | 3 | 3 | 97.4 | |||||
monocyte count | 2 | 2 | 2 | 95.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
creatine kinase measurement | 7 | 98.4 | |||||
mean platelet volume | 5 | 98 | |||||
platelet count | 5 | 2.6 | 97.9 | ||||
leukocyte count | 3 | 97.4 | |||||
monocyte count | 2 | 95.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | creatine kinase, M-type | VGNC:7552 | 744935 | |||||
Mouse | MGI:88413 | 12715 | ||||||
Rat | RGD:2358 | 24265 | ||||||
Dog | creatine kinase, M-type | VGNC:39291 | 476435 | |||||
Horse | creatine kinase, M-type | VGNC:16564 | 100065641 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | creatine kinase, M-type | |||||
Mouse | ||||||
Rat | ||||||
Dog | creatine kinase, M-type | |||||
Horse | creatine kinase, M-type | |||||
PMID | Text |
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