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Tbio
CIZ1
Cip1-interacting zinc finger protein

Protein Summary
Description
May regulate the subcellular localization of CIP/WAF1. The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372938
  • ENSP00000362029
  • ENSG00000148337
  • ENST00000372948
  • ENSP00000362039
  • ENST00000372954
  • ENSP00000362045
  • ENST00000629610
  • ENSP00000486816
  • ENST00000634901
  • ENSP00000489425

Symbol
  • LSFR1
  • NP94
  • ZNF356
  • NP94
  • LSFR1
  • ZNF356
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
transcription factor
0.81
transcription factor binding site profile
0.8
tissue
0.77
cell type or tissue
0.76


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.22   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.22   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (64)
L3MBTL2
Tbio
Family:  Epigenetic
Novelty:  0.11193867
p_int:  0.99999883
p_ni:  0.00000117
Data Source:  BioPlex
ERH
Tbio
Novelty:  0.00711649
p_int:  0.999998368
p_ni:  0.000001632
p_wrong:  1e-9
Score:  0.799
Data Source:  BioPlex,STRINGDB
BCL7C
Tdark
Novelty:  0.31203802
p_int:  0.999998011
p_ni:  0.000001989
Data Source:  BioPlex
CHTOP
Tbio
Novelty:  0.04170391
p_int:  0.999996246
p_ni:  0.000003754
Data Source:  BioPlex
CCDC97
Tdark
Novelty:  2.36351796
p_int:  0.99987005
p_ni:  0.00012995
Score:  0.173
Data Source:  BioPlex,STRINGDB
TMED7
Tdark
Novelty:  0.31193294
p_int:  0.999157844
p_ni:  0.000842152
p_wrong:  4e-9
Data Source:  BioPlex
ACP5
Tbio
Family:  Enzyme
Novelty:  0.00034703
p_int:  0.993360611
p_ni:  0.006639389
Score:  0.325
Data Source:  BioPlex,STRINGDB
SAFB2
Tbio
Novelty:  0.12354864
p_int:  0.992865847
p_ni:  0.007134129
p_wrong:  2.4e-8
Score:  0.546
Data Source:  BioPlex,STRINGDB
EDA
Tbio
Novelty:  0.00352464
p_int:  0.916563206
p_ni:  0.083425558
p_wrong:  0.000011236
Data Source:  BioPlex
KLHL22
Tbio
Novelty:  0.24456252
p_int:  0.916001216
p_ni:  0.083996175
p_wrong:  0.000002609
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
6
4
6
77.5
body height
1
1
1
44.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
6
77.5
body height
1
44.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
CDKN1A interacting zinc finger protein 1
717725
Mouse
MGI:1920234
68379
Rat
RGD:1305336
296639
Dog
CDKN1A interacting zinc finger protein 1
VGNC:39285
480709
Horse
CDKN1A interacting zinc finger protein 1
VGNC:16559
100070290
Species
Name
OMA
EggNOG
Inparanoid
Macaque
CDKN1A interacting zinc finger protein 1
Mouse
Rat
Dog
CDKN1A interacting zinc finger protein 1
Horse
CDKN1A interacting zinc finger protein 1
Publication Statistics
PubMed Score 38.22
PubMed score by year
PubTator Score 28.09
PubTator score by year
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Related Publications
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PMID
Year
Title