CITED2
Cbp/p300-interacting transactivator 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 1 | ||
transcription factor binding site profile | 0.99 | ||
biological process | 0.98 | ||
transcription factor perturbation | 0.94 | ||
disease perturbation | 0.87 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of the TFAP2 (AP-2) family of transcription factors | ||||
Reactome | Cellular response to hypoxia | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Cellular responses to stress | ||||
Reactome | FOXO-mediated transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of the TFAP2 (AP-2) family of transcription factors | ||||
Cellular response to hypoxia | ||||
Cellular responses to external stimuli | ||||
Cellular responses to stress | ||||
FOXO-mediated transcription | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum non-albumin protein measurement | 2 | 3 | 3 | 66.8 | |||||
heel bone mineral density | 2 | 2 | 2 | 59.5 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 53.3 | |||||
mean corpuscular volume | 1 | 1 | 1 | 42.3 | |||||
albumin:globulin ratio measurement | 1 | 1 | 1 | 8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum non-albumin protein measurement | 3 | 66.8 | |||||
heel bone mineral density | 2 | 59.5 | |||||
mean reticulocyte volume | 1 | 53.3 | |||||
mean corpuscular volume | 1 | 42.3 | |||||
albumin:globulin ratio measurement | 1 | 8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | 707729 | ||||||
Mouse | MGI:1306784 | 17684 | ||||||
Rat | RGD:620112 | 114490 | ||||||
Dog | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | VGNC:39284 | 484010 | |||||
Cow | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | VGNC:27377 | 521378 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | |||||
Cow | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 | |||||
PMID | Year | Title |
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