Tbio CIP2A Protein CIP2A

Protein Summary

Description

Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.

Uniprot Accession IDs

• Q8TCG1
• A1L4J7
• B9EGC3
• Q6P4G6
• Q8WVP8
• Q96PI2
• Q9H9C6
• Q9P204

Gene Name

• CIP2A

Ensembl ID

• ENST00000295746
• ENSP00000295746
• ENSG00000163507
• ENST00000491772
• ENSP00000419487

Symbol

• KIAA1524
• p90
• KIAA1524

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 199.62   (req: < 5)

Gene RIFs: 132   (req: <= 3)

Antibodies: 217   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 199.62   (req: >= 5)

Gene RIFs: 132   (req: > 3)

Antibodies: 217   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0