Tbio CHURC1 Protein Churchill

Protein Summary

Description

Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself.

Uniprot Accession IDs

• Q8WUH1
• B3KQ81
• G3V1X3
• G3V214
• Q9H3K7

Gene Name

• CHURC1

Ensembl ID

• ENST00000548752
• ENSP00000450165
• ENSG00000258289
• ENST00000549115
• ENSP00000448050
• ENST00000607599
• ENSP00000475473

Symbol

• C14orf52
• CHCH
• chch
• My015
• C14orf52

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.78
histone modification site profile	0.73
microRNA	0.66
tissue sample	0.63
small molecule perturbation	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.48   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 55   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.48   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0