Protein Summary
Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself.
- ENST00000548752
- ENSP00000450165
- ENSG00000258289
- ENST00000549115
- ENSP00000448050
- ENST00000607599
- ENSP00000475473
- C14orf52
- CHCH
- chch
- My015
- C14orf52
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.78 | ||
histone modification site profile | 0.73 | ||
microRNA | 0.66 | ||
tissue sample | 0.63 | ||
small molecule perturbation | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.25 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 55 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 21.25 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 55 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (55)
NMT2
Family: Enzyme
Novelty: 0.04826835
p_int: 0.999998282
p_ni: 0.000001718
Data Source: BioPlex
NMT1
Family: Enzyme
Novelty: 0.00343834
p_int: 0.999420116
p_ni: 0.000579884
Data Source: BioPlex
ACTR3B
Novelty: 0.06033214
p_int: 0.998993393
p_ni: 6.3e-8
p_wrong: 0.001006544
Score: 0.286
Data Source: BioPlex,STRINGDB
UBB
Novelty: 0.00661254
p_int: 0.997574715
p_ni: 0.002424848
p_wrong: 4.37e-7
Data Source: BioPlex
MTMR14
Family: Enzyme
Novelty: 0.07074944
p_int: 0.996234934
p_ni: 0.003765064
p_wrong: 1e-9
Data Source: BioPlex
CREBBP
Family: Epigenetic
Novelty: 0.00111166
p_int: 0.765868302
p_ni: 0.233687647
p_wrong: 0.000444051
Data Source: BioPlex
GLRX
Novelty: 0.00111903
p_int: 0.757488791
p_ni: 0.008064526
p_wrong: 0.234446684
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (3)
Functions (1)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (17)
Items per page:
1 – 5 of 17
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular volume | 2 | 6 | 6 | 97.3 | |||||
reticulocyte count | 2 | 3 | 4 | 96.4 | |||||
reticulocyte measurement | 3 | 3 | 5 | 96.4 | |||||
mean reticulocyte volume | 1 | 4 | 4 | 94.5 | |||||
red blood cell distribution width | 2 | 2 | 2 | 89.4 | |||||
Items per page:
1 – 5 of 17
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular volume | 6 | 97.3 | |||||
reticulocyte count | 4 | 96.4 | |||||
reticulocyte measurement | 5 | 96.4 | |||||
mean reticulocyte volume | 4 | 94.5 | |||||
red blood cell distribution width | 2 | 89.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:1923684 | 211151 | ||||||
Rat | RGD:1305116 | 299154 | ||||||
Dog | churchill domain containing 1 | VGNC:39262 | 609942 | |||||
Horse | churchill domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20099] | |||||||
Cow | churchill domain containing 1 | VGNC:27355 | 616539 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | churchill domain containing 1 | |||||
Horse | churchill domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20099] | |||||
Cow | churchill domain containing 1 | |||||
Publication Statistics
PubMed Score 21.25
PubMed score by year
PubTator Score 102.02
PubTator score by year
Related Publications
Text Mined References (7)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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