CHMP4B
Charged multivesicular body protein 4b
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.95 | ||
biological process | 0.91 | ||
interacting protein | 0.9 | ||
virus perturbation | 0.83 | ||
transcription factor binding site profile | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Autophagy | ||||
Reactome | Budding and maturation of HIV virion | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Disease | ||||
Reactome | Endosomal Sorting Complex Required For Transport (ESCRT) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Autophagy | ||||
Budding and maturation of HIV virion | ||||
Cellular responses to external stimuli | ||||
Disease | ||||
Endosomal Sorting Complex Required For Transport (ESCRT) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body height | 2 | 2 | 2 | 91.5 | |||||
suntan | 1 | 1 | 1 | 88.2 | |||||
BMI-adjusted hip circumference | 2 | 6 | 6 | 84.9 | |||||
non-melanoma skin carcinoma | 1 | 2 | 0 | 1.3 | 68 | ||||
anthropometric measurement | 1 | 1 | 0 | 1.2 | 62.1 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body height | 2 | 91.5 | |||||
suntan | 1 | 88.2 | |||||
BMI-adjusted hip circumference | 6 | 84.9 | |||||
non-melanoma skin carcinoma | 0 | 1.3 | 68 | ||||
anthropometric measurement | 0 | 1.2 | 62.1 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | charged multivesicular body protein 4B | VGNC:6080 | 747134 | |||||
Macaque | charged multivesicular body protein 4B | 709004 | ||||||
Mouse | MGI:1922858 | 75608 | ||||||
Rat | RGD:1583604 | 679886 | ||||||
Dog | charged multivesicular body protein 4B | VGNC:54643 | 485842 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | charged multivesicular body protein 4B | |||||
Macaque | charged multivesicular body protein 4B | |||||
Mouse | ||||||
Rat | ||||||
Dog | charged multivesicular body protein 4B | |||||
PMID | Year | Title |
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