CHD8
Chromodomain-helicase-DNA-binding protein 8
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 1 | ||
protein domain | 0.97 | ||
disease perturbation | 0.96 | ||
interacting protein | 0.91 | ||
biological process | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Deactivation of the beta-catenin transactivating complex | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by WNT | ||||
Reactome | TCF dependent signaling in response to WNT | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Deactivation of the beta-catenin transactivating complex | ||||
Signal Transduction | ||||
Signaling by WNT | ||||
TCF dependent signaling in response to WNT | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body height | 1 | 1 | 1 | 77.9 | |||||
self reported educational attainment | 1 | 1 | 1 | 59 | |||||
BMI-adjusted hip circumference | 1 | 1 | 1 | 47.7 | |||||
mathematical ability | 1 | 1 | 1 | 35 | |||||
smoking status measurement | 1 | 1 | 1 | 15.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body height | 1 | 77.9 | |||||
self reported educational attainment | 1 | 59 | |||||
BMI-adjusted hip circumference | 1 | 47.7 | |||||
mathematical ability | 1 | 35 | |||||
smoking status measurement | 1 | 15.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | chromodomain helicase DNA binding protein 8 | VGNC:3449 | 739837 | |||||
Macaque | chromodomain helicase DNA binding protein 8 | 708169 | ||||||
Mouse | MGI:1915022 | 67772 | ||||||
Rat | RGD:620696 | 65027 | ||||||
Dog | chromodomain helicase DNA binding protein 8 | VGNC:39206 | 475401 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | chromodomain helicase DNA binding protein 8 | |||||
Macaque | chromodomain helicase DNA binding protein 8 | |||||
Mouse | ||||||
Rat | ||||||
Dog | chromodomain helicase DNA binding protein 8 | |||||
PMID | Year | Title |
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