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Tdark
CFAP77
Cilia- and flagella-associated protein 77

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000343036
  • ENSP00000343290
  • ENSG00000188523
  • ENST00000393216
  • ENSP00000376909

Symbol
  • C9orf171
  • C9orf171
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 23   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 23   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (20)
TUBA3C
Tchem
Novelty:  0.0187396
p_int:  0.99129948
p_ni:  0.00870052
Score:  0.292
Data Source:  BioPlex,STRINGDB
CCDC28A
Tdark
Novelty:  0.47441753
Score:  0.586
Data Source:  STRINGDB
FAM153A
Tdark
Novelty:  16.01889363
Score:  0.557
Data Source:  STRINGDB
MTMR8
Tbio
Family:  Enzyme
Novelty:  0.37417853
Score:  0.555
Data Source:  STRINGDB
FAM153B
Tdark
Novelty:  4.34922003
Score:  0.55
Data Source:  STRINGDB
DEUP1
Tbio
Novelty:  0.13274391
Score:  0.529
Data Source:  STRINGDB
SLC25A43
Tbio
Family:  Transporter
Novelty:  0.21667475
Score:  0.526
Data Source:  STRINGDB
CCSER1
Tbio
Novelty:  0.20244518
Score:  0.511
Data Source:  STRINGDB
TTC28
Tdark
Novelty:  0.16651519
Score:  0.511
Data Source:  STRINGDB
FBXL7
Tbio
Novelty:  0.10670779
Score:  0.479
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
2
2
77.9
self reported educational attainment
2
2
2
68.7
mood instability measurement
1
1
1
61.2
irritability measurement
1
1
0
7
57.8
type 2 diabetes mellitus
1
1
0
2.9
51.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
2
77.9
self reported educational attainment
2
68.7
mood instability measurement
1
61.2
irritability measurement
0
7
57.8
type 2 diabetes mellitus
0
2.9
51.3
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 77
VGNC:4661
464913
Macaque
cilia and flagella associated protein 77
106993584
Mouse
MGI:2685669
329375
Rat
RGD:1564114
499765
Dog
cilia and flagella associated protein 77
VGNC:51940
102153503
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 77
Macaque
cilia and flagella associated protein 77
Mouse
Rat
Dog
cilia and flagella associated protein 77
Publication Statistics
PubMed Score 0.46
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title