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Tbio
CFAP52
Cilia- and flagella-associated protein 52

Protein Summary
Description
May play a role in cell growth and/or survival. WD repeat-containing proteins, such as WDR16, play crucial roles in a wide range of physiologic functions, including signal transduction, RNA processing, remodeling the cytoskeleton, regulation of vesicular traffic, and cell division (Silva et al., 2005 [PubMed 15967112]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000352665
  • ENSP00000339449
  • ENSG00000166596
  • ENST00000396219
  • ENSP00000379521

Symbol
  • WDR16
  • WDRPUH
  • WDR16
  • WDRPUH
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.76
protein domain
0.73
transcription factor binding site profile
0.63
tissue sample
0.52
transcription factor
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.34   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.34   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
CRYZL1
Tbio
Family:  Enzyme
Novelty:  0.04435286
p_int:  0.999385431
p_ni:  0.000564325
p_wrong:  0.000050245
Score:  0.214
Data Source:  BioPlex,STRINGDB
ASMTL
Tbio
Family:  Enzyme
Novelty:  0.17725871
p_int:  0.919039847
p_ni:  0.080960153
Score:  0.351
Data Source:  BioPlex,STRINGDB
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.83528694
p_ni:  0.16471306
Score:  0.346
Data Source:  BioPlex,STRINGDB
STIP1
Tbio
Novelty:  0.00590952
p_int:  0.786719314
p_ni:  0.213280686
Score:  0.319
Data Source:  BioPlex,STRINGDB
CCT6A
Tbio
Novelty:  0.02368046
p_int:  0.772008111
p_ni:  0.227991889
Score:  0.374
Data Source:  BioPlex,STRINGDB
CLTCL1
Tbio
Novelty:  0.05667807
p_int:  0.767447488
p_ni:  0.232552479
p_wrong:  3.3e-8
Score:  0.183
Data Source:  BioPlex,STRINGDB
CCT4
Tbio
Novelty:  0.01176123
Score:  0.906
Data Source:  STRINGDB
TCP1
Tbio
Novelty:  0.00395241
Score:  0.811
Data Source:  STRINGDB
CCDC113
Tdark
Novelty:  1.10748096
Score:  0.761
Data Source:  STRINGDB
BBS10
Tbio
Novelty:  0.03343798
Score:  0.733
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
1
4
83.6
alkaline phosphatase measurement
2
1
1
8.4
80.2
cortical thickness
1
1
0
7.3
48
blood protein measurement
1
1
1
42.1
gut microbiome measurement
1
1
1
23.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
83.6
alkaline phosphatase measurement
1
8.4
80.2
cortical thickness
0
7.3
48
blood protein measurement
1
42.1
gut microbiome measurement
1
23.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 52
VGNC:9232
100614756
Macaque
cilia and flagella associated protein 52
722040
Mouse
MGI:1919110
71860
Rat
RGD:1308151
303233
Dog
cilia and flagella associated protein 52
VGNC:39164
479500
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 52
Macaque
cilia and flagella associated protein 52
Mouse
Rat
Dog
cilia and flagella associated protein 52
Publication Statistics
PubMed Score 6.34
PubMed score by year
PubTator Score 2.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title