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Tdark
CFAP36
Cilia- and flagella-associated protein 36

Protein Summary
Description
May act as an effector for ARL3.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339012
  • ENSP00000342699
  • ENSG00000163001
  • ENST00000349456
  • ENSP00000295117

Symbol
  • CCDC104
  • BARTL1
  • CCDC104
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
tissue
0.68
tissue sample
0.61
transcription factor
0.59
cell line
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.54   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.54   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
ARL2
Tbio
Family:  Enzyme
Novelty:  0.01989908
p_int:  0.999996203
p_ni:  0.000003774
p_wrong:  2.3e-8
Score:  0.574
Data Source:  BioPlex,STRINGDB
OSBPL9
Tbio
Novelty:  0.07633459
p_int:  0.998945984
p_ni:  0.001054014
p_wrong:  2e-9
Score:  0.197
Data Source:  BioPlex,STRINGDB
SNTB2
Tbio
Novelty:  0.05469501
p_int:  0.9959379
p_ni:  0.004062095
p_wrong:  5e-9
Score:  0.187
Data Source:  BioPlex,STRINGDB
KCTD10
Tbio
Novelty:  0.10573929
p_int:  0.916945418
p_ni:  0.083054582
Score:  0.163
Data Source:  BioPlex,STRINGDB
BDH2
Tbio
Family:  Enzyme
Novelty:  0.04118875
p_int:  0.866010706
p_ni:  0.133989282
p_wrong:  1.2e-8
Score:  0.209
Data Source:  BioPlex,STRINGDB
ARL3
Tbio
Family:  Enzyme
Novelty:  0.01954965
Score:  0.947
Data Source:  STRINGDB
ARL13B
Tbio
Family:  Enzyme
Novelty:  0.01481674
Score:  0.822
Data Source:  STRINGDB
TTC29
Tdark
Novelty:  0.1887357
Score:  0.746
Data Source:  STRINGDB
CCDC63
Tbio
Novelty:  0.11520913
Score:  0.74
Data Source:  STRINGDB
RIBC2
Tdark
Novelty:  0.0209935
Score:  0.712
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.5
71.3
diastolic blood pressure
1
1
1
33.1
metabolic syndrome
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.5
71.3
diastolic blood pressure
1
33.1
metabolic syndrome
1
15.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 36
VGNC:206
459245
Macaque
cilia and flagella associated protein 36
677698
Mouse
MGI:1913994
216618
Rat
RGD:1311732
289859
Dog
cilia and flagella associated protein 36
VGNC:39161
474602
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 36
Macaque
cilia and flagella associated protein 36
Mouse
Rat
Dog
cilia and flagella associated protein 36
Publication Statistics
PubMed Score 2.54
PubMed score by year
PubTator Score 2.50
PubTator score by year
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Related Publications
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PMID
Year
Title