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Tdark
CFAP161
Cilia- and flagella-associated protein 161

Protein Summary
Description
May play a role in motile cilia function, possibly by acting on dynein arm assembly.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000286732
  • ENSP00000286732
  • ENSG00000156206

Symbol
  • C15orf26
  • C15orf26
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.15   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 39   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.15   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 39   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
TLNRD1
Tdark
Novelty:  0.26211075
Score:  0.73
Data Source:  STRINGDB
USP36
Tbio
Family:  Enzyme
Novelty:  0.02779727
Score:  0.694
Data Source:  STRINGDB
TMC3
Tdark
Family:  IC
Novelty:  0.23776276
Score:  0.659
Data Source:  STRINGDB
WSCD1
Tdark
Novelty:  0.70877323
Score:  0.623
Data Source:  STRINGDB
IL16
Tbio
Novelty:  0.0023276
Score:  0.591
Data Source:  STRINGDB
ACTRT3
Tdark
Novelty:  0.36920501
Score:  0.563
Data Source:  STRINGDB
ACTRT2
Tdark
Novelty:  0.38919779
Score:  0.546
Data Source:  STRINGDB
ERICH1
Tdark
Novelty:  1.30496362
Score:  0.543
Data Source:  STRINGDB
UTP15
Tbio
Novelty:  0.08174586
Score:  0.543
Data Source:  STRINGDB
MYCBPAP
Tbio
Novelty:  1.11929455
Score:  0.53
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair color
2
2
0
1.1
92.9
1
1
1
39.6
high density lipoprotein cholesterol measurement
1
1
1
17.8
electrocardiography
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair color
0
1.1
92.9
1
39.6
high density lipoprotein cholesterol measurement
1
17.8
electrocardiography
1
15.8
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 161
VGNC:3565
453588
Macaque
cilia and flagella associated protein 161
713184
Mouse
MGI:1922806
75556
Rat
RGD:1310371
308794
Dog
cilia and flagella associated protein 161
VGNC:39158
610056
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cilia and flagella associated protein 161
Macaque
cilia and flagella associated protein 161
Mouse
Rat
Dog
cilia and flagella associated protein 161
Publication Statistics
PubMed Score 1.15
PubMed score by year
PubTator Score 0.17
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title