CERS2
Ceramide synthase 2
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.98 | ||
cellular component | 0.79 | ||
transcription factor perturbation | 0.74 | ||
microRNA | 0.69 | ||
PubMedID | 0.64 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Sphingolipid de novo biosynthesis | ||||
Reactome | Sphingolipid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of lipids | ||||
Sphingolipid de novo biosynthesis | ||||
Sphingolipid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 8 | 5 | 8 | 9.2 | 97.1 | ||||
apolipoprotein A 1 measurement | 2 | 3 | 3 | 95.6 | |||||
sex hormone-binding globulin measurement | 6 | 2 | 6 | 89.7 | |||||
creatinine measurement | 4 | 4 | 5 | 88.9 | |||||
high density lipoprotein cholesterol measurement | 3 | 2 | 3 | 85 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 8 | 9.2 | 97.1 | ||||
apolipoprotein A 1 measurement | 3 | 95.6 | |||||
sex hormone-binding globulin measurement | 6 | 89.7 | |||||
creatinine measurement | 5 | 88.9 | |||||
high density lipoprotein cholesterol measurement | 3 | 85 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ceramide synthase 2 | VGNC:495 | 469482 | |||||
Macaque | ceramide synthase 2 | 716180 | ||||||
Mouse | MGI:1924143 | 76893 | ||||||
Rat | RGD:1310059 | 310667 | ||||||
Dog | ceramide synthase 2 | VGNC:39148 | 483187 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ceramide synthase 2 | |||||
Macaque | ceramide synthase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ceramide synthase 2 | |||||
PMID | Year | Title |
---|