You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
CERCAM
Inactive glycosyltransferase 25 family member 3

Protein Summary
Description
Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier. Does not express any beta-galactosyltransferase activity in vitro.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372838
  • ENSP00000361929
  • ENSG00000167123
  • ENST00000372842
  • ENSP00000361933

Symbol
  • CEECAM1
  • GLT25D3
  • KIAA1502
  • CEECAM1
  • GLT25D3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
disease perturbation
0.79
cell line
0.63
tissue
0.57
transcription factor
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.49   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 105   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.49   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
CCT3
Tbio
Novelty:  0.01642521
p_int:  0.998402165
p_ni:  0.001597836
Data Source:  BioPlex
CCT6B
Tdark
Novelty:  0.28933315
p_int:  0.996560694
p_ni:  0.003439306
Data Source:  BioPlex
SLAMF1
Tbio
Novelty:  0.00112892
p_int:  0.995027138
p_ni:  0.004972862
Data Source:  BioPlex
INSL5
Tbio
Novelty:  0.04351334
p_int:  0.994748547
p_ni:  0.005251453
Data Source:  BioPlex
CCT2
Tbio
Novelty:  0.01967139
p_int:  0.992616526
p_ni:  0.007383474
Data Source:  BioPlex
CCT7
Tbio
Novelty:  0.02247038
p_int:  0.99229791
p_ni:  0.00770209
Data Source:  BioPlex
TCP1
Tbio
Novelty:  0.00395241
p_int:  0.988384736
p_ni:  0.011615264
Data Source:  BioPlex
OS9
Tbio
Novelty:  0.01490339
p_int:  0.986515491
p_ni:  0.013484509
Score:  0.33
Data Source:  BioPlex,STRINGDB
IDS
Tbio
Family:  Enzyme
Novelty:  0.00733996
p_int:  0.986044584
p_ni:  0.013955416
Data Source:  BioPlex
CCT6A
Tbio
Novelty:  0.02368046
p_int:  0.982386896
p_ni:  0.017613104
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
pulse pressure measurement
1
1
1
9.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
pulse pressure measurement
1
9.1
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cerebral endothelial cell adhesion molecule
VGNC:4659
741072
Mouse
MGI:2139134
99151
Rat
RGD:1304778
296616
Dog
cerebral endothelial cell adhesion molecule
VGNC:39146
609012
Horse
cerebral endothelial cell adhesion molecule
VGNC:16436
100070231
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cerebral endothelial cell adhesion molecule
Mouse
Rat
Dog
cerebral endothelial cell adhesion molecule
Horse
cerebral endothelial cell adhesion molecule
Publication Statistics
PubMed Score 3.49
PubMed score by year
PubTator Score 2.30
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title