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Tbio
CEP128
Centrosomal protein of 128 kDa

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000216517
  • ENSP00000216517
  • ENSG00000100629
  • ENST00000281129
  • ENSP00000281129
  • ENST00000555265
  • ENSP00000451162

Symbol
  • C14orf145
  • C14orf61
  • C14orf61
  • LEDP/132
  • C14orf145
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.75
microRNA
0.7
cell type or tissue
0.68
cell line
0.65
virus perturbation
0.64


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.77   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.77   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
TSNAX
Tbio
Novelty:  0.00888891
p_int:  0.999999975
p_ni:  1.7e-8
p_wrong:  7e-9
Score:  0.332
Data Source:  BioPlex,STRINGDB
INKA2
Tdark
Novelty:  0.57898295
p_int:  0.999988334
p_ni:  0.000003978
p_wrong:  0.000007688
Score:  0.54
Data Source:  BioPlex,STRINGDB
S100A4
Tchem
Novelty:  0.00136919
p_int:  0.999706321
p_ni:  0.000051052
p_wrong:  0.000242626
Data Source:  BioPlex
GTF2A1
Tchem
Novelty:  0.19577296
Score:  0.834
Data Source:  STRINGDB
CEP170
Tbio
Novelty:  0.05342931
Score:  0.814
Data Source:  STRINGDB
NIN
Tbio
Novelty:  0.01312714
Score:  0.805
Data Source:  STRINGDB
ODF2
Tbio
Novelty:  0.03203587
Score:  0.784
Data Source:  STRINGDB
CNTRL
Tbio
Novelty:  0.01245179
Score:  0.779
Data Source:  STRINGDB
DCTN1
Tbio
Novelty:  0.00494896
Score:  0.736
Data Source:  STRINGDB
CEP89
Tbio
Novelty:  0.17461805
Score:  0.734
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
0
1.4
91.7
albuminuria
1
1
0
30.7
39.6
response to radiation
1
1
0
1.5
28.1
radiation-induced brain injury
1
1
0
1.5
28.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.4
91.7
albuminuria
0
30.7
39.6
response to radiation
0
1.5
28.1
radiation-induced brain injury
0
1.5
28.1
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
centrosomal protein 128
VGNC:3451
467522
Macaque
centrosomal protein 128
707594
Mouse
MGI:1922466
75216
Dog
centrosomal protein 128
VGNC:39117
490814
Cow
centrosomal protein 128
VGNC:53080
529746
Species
Name
OMA
EggNOG
Inparanoid
Chimp
centrosomal protein 128
Macaque
centrosomal protein 128
Mouse
Dog
centrosomal protein 128
Cow
centrosomal protein 128
Publication Statistics
PubMed Score 6.77
PubMed score by year
PubTator Score 1.35
PubTator score by year
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Related Publications
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PMID
Year
Title