CENPA
Histone H3-like centromeric protein A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.96 | ||
transcription factor perturbation | 0.91 | ||
histone modification site profile | 0.85 | ||
transcription factor binding site profile | 0.83 | ||
disease perturbation | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Reactome | Amplification of signal from the kinetochores | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle Checkpoints | ||||
Reactome | Cell Cycle, Mitotic | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Amplification of signal from the kinetochores | ||||
Cell Cycle | ||||
Cell Cycle Checkpoints | ||||
Cell Cycle, Mitotic | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
diastolic blood pressure | 5 | 5 | 8 | 89.9 | |||||
triglyceride measurement | 2 | 3 | 3 | 89.4 | |||||
2 | 5 | 5 | 88.6 | ||||||
C-reactive protein measurement | 2 | 3 | 4 | 84 | |||||
Calcium channel blocker use measurement | 1 | 1 | 1 | 80 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
diastolic blood pressure | 8 | 89.9 | |||||
triglyceride measurement | 3 | 89.4 | |||||
5 | 88.6 | ||||||
C-reactive protein measurement | 4 | 84 | |||||
Calcium channel blocker use measurement | 1 | 80 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | centromere protein A | VGNC:191 | 459086 | |||||
Macaque | centromere protein A | 697312 | ||||||
Mouse | MGI:88375 | 12615 | ||||||
Rat | RGD:1563607 | 298850 | ||||||
Dog | centromere protein A | VGNC:39101 | 475692 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | centromere protein A | |||||
Macaque | centromere protein A | |||||
Mouse | ||||||
Rat | ||||||
Dog | centromere protein A | |||||
PMID | Year | Title |
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