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Tchem
CDK18
Cyclin-dependent kinase 18

Protein Summary
Description
May play a role in signal transduction cascades in terminally differentiated cells.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360066
  • ENSP00000353176
  • ENSG00000117266
  • ENST00000429964
  • ENSP00000399082
  • ENST00000506784
  • ENSP00000423665

Symbol
  • PCTAIRE3
  • PCTK3
  • PCTK3
  • PCTAIRE
  • PCTAIRE3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
1
molecular function
0.94
disease perturbation
0.87
gene perturbation
0.8
protein domain
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.01   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 175   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.01   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 175   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0