Protein Summary
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion.
- ENST00000267383
- ENSP00000267383
- ENSG00000139880
- ENST00000397359
- ENSP00000380517
- ENST00000487137
- ENSP00000434821
- ENST00000554034
- ENSP00000452493
- CDH11L
- CDH11L
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.76 | ||
cell line | 0.73 | ||
protein domain | 0.73 | ||
tissue sample | 0.63 | ||
transcription factor binding site profile | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.27 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 111 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.27 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 111 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (44)
CTNNA3
Novelty: 0.01472452
p_int: 0.999999025
p_ni: 5.8e-8
p_wrong: 9.17e-7
Score: 0.355
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (8)
Reactome (4)
PathwayCommons (2)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Adherens junctions interactions | ||||
Reactome | Cell junction organization | ||||
Reactome | Cell-Cell communication | ||||
Reactome | Cell-cell junction organization | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Adherens junctions interactions | ||||
Cell junction organization | ||||
Cell-Cell communication | ||||
Cell-cell junction organization | ||||
Viral Interactions (0)
Gene Ontology Terms (19)
Functions (7)
Components (6)
Processes (6)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (24)
Items per page:
1 – 5 of 24
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
red blood cell distribution width | 6 | 6 | 10 | 99.4 | |||||
eosinophil count | 3 | 5 | 7 | 98 | |||||
basophil count | 5 | 7 | 9 | 98 | |||||
eosinophil percentage of leukocytes | 2 | 7 | 9 | 97 | |||||
reticulocyte count | 6 | 3 | 6 | 97 | |||||
Items per page:
1 – 5 of 24
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
red blood cell distribution width | 10 | 99.4 | |||||
eosinophil count | 7 | 98 | |||||
basophil count | 9 | 98 | |||||
eosinophil percentage of leukocytes | 9 | 97 | |||||
reticulocyte count | 6 | 97 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | cadherin 24 | VGNC:7436 | 467403 | |||||
Macaque | cadherin 24 | 713241 | ||||||
Mouse | MGI:1928330 | 239096 | ||||||
Rat | RGD:1560161 | 498515 | ||||||
Dog | cadherin 24 | VGNC:39031 | 100855685 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | cadherin 24 | |||||
Macaque | cadherin 24 | |||||
Mouse | ||||||
Rat | ||||||
Dog | cadherin 24 | |||||
Publication Statistics
PubMed Score 2.27
PubMed score by year
PubTator Score 1.86
PubTator score by year
Related Publications
Text Mined References (6)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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