Tbio CDH24 Cadherin-24

Protein Summary

Description

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion.

Uniprot Accession IDs

• Q86UP0
• D3DS44
• Q86UP1
• Q9NT84

Gene Name

• CDH24

Ensembl ID

• ENST00000267383
• ENSP00000267383
• ENSG00000139880
• ENST00000397359
• ENSP00000380517
• ENST00000487137
• ENSP00000434821
• ENST00000554034
• ENSP00000452493

Symbol

• CDH11L
• CDH11L

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.76
cell line	0.73
protein domain	0.73
tissue sample	0.63
transcription factor binding site profile	0.6

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 111   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.88   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0