CDC16
Cell division cycle protein 16 homolog
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.98 | ||
biological process | 0.94 | ||
disease perturbation | 0.93 | ||
cellular component | 0.91 | ||
kinase perturbation | 0.91 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | APC-Cdc20 mediated degradation of Nek2A | ||||
Reactome | APC/C-mediated degradation of cell cycle proteins | ||||
Reactome | APC/C:Cdc20 mediated degradation of Cyclin B | ||||
Reactome | APC/C:Cdc20 mediated degradation of Securin | ||||
Reactome | APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
APC-Cdc20 mediated degradation of Nek2A | ||||
APC/C-mediated degradation of cell cycle proteins | ||||
APC/C:Cdc20 mediated degradation of Cyclin B | ||||
APC/C:Cdc20 mediated degradation of Securin | ||||
APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | LIFEdb | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 2 | 3 | 94.4 | |||||
sex hormone-binding globulin measurement | 3 | 2 | 3 | 82 | |||||
eosinophil count | 2 | 2 | 2 | 78.2 | |||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 68.3 | |||||
leukocyte count | 1 | 1 | 1 | 61.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
lymphocyte count | 3 | 94.4 | |||||
sex hormone-binding globulin measurement | 3 | 82 | |||||
eosinophil count | 2 | 78.2 | |||||
eosinophil percentage of leukocytes | 1 | 68.3 | |||||
leukocyte count | 1 | 61.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | cell division cycle 16 | VGNC:51842 | 452688 | |||||
Macaque | cell division cycle 16 | 699089 | ||||||
Mouse | MGI:1917207 | 69957 | ||||||
Rat | RGD:1305076 | 290875 | ||||||
Dog | cell division cycle 16 | 607100 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | cell division cycle 16 | |||||
Macaque | cell division cycle 16 | |||||
Mouse | ||||||
Rat | ||||||
Dog | cell division cycle 16 | |||||
PMID | Year | Title |
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