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Tbio
CDAN1
Codanin-1

Protein Summary
Description
May act as a negative regulator of ASF1 in chromatin assembly. This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356231
  • ENSP00000348564
  • ENSG00000140326

Symbol
  • DLT
  • CDA1
  • CDAI
  • CDAN1A
  • PRO1295
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.79
histone modification site profile
0.73
tissue
0.56
tissue sample
0.56
cell type or tissue
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 174.73   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 174.73   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (46)
ASF1B
Tbio
Novelty:  0.05716701
p_int:  0.999999996
p_ni:  3e-9
p_wrong:  1e-9
Score:  0.707
Data Source:  BioPlex,STRINGDB
ASF1A
Tchem
Novelty:  0.02544466
p_int:  0.999999993
p_ni:  6e-9
p_wrong:  1e-9
Score:  0.663
Data Source:  BioPlex,STRINGDB
MAMDC2
Tdark
Novelty:  0.22933145
p_int:  0.997387179
p_ni:  0.00260165
p_wrong:  0.000011172
Score:  0.622
Data Source:  BioPlex,STRINGDB
SEC23B
Tbio
Novelty:  0.02307622
Score:  0.802
Data Source:  STRINGDB
STRC
Tbio
Novelty:  0.01587212
Score:  0.718
Data Source:  STRINGDB
CATSPER2
Tchem
Family:  IC
Novelty:  0.03701031
Score:  0.716
Data Source:  STRINGDB
KLF1
Tbio
Family:  TF
Novelty:  0.00370238
Score:  0.711
Data Source:  STRINGDB
C15orf41
Tbio
Novelty:  0.11812699
Score:  0.706
Data Source:  STRINGDB
OR11A1
Tdark
Family:  oGPCR
Novelty:  1.40790586
Score:  0.702
Data Source:  STRINGDB
DLAT
Tbio
Family:  Enzyme
Novelty:  0.00311191
Score:  0.669
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
1
1
2
79.8
high density lipoprotein cholesterol measurement
1
1
2
68
hematocrit
1
1
1
38.2
IGF-1 measurement
1
1
1
33.1
bipolar I disorder
1
1
0
1.1
3.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
2
79.8
high density lipoprotein cholesterol measurement
2
68
hematocrit
1
38.2
IGF-1 measurement
1
33.1
bipolar I disorder
0
1.1
3.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
codanin 1
VGNC:3568
741717
Macaque
codanin 1
708838
Mouse
MGI:1916218
68968
Rat
RGD:1306771
311348
Dog
codanin 1 [Source:HGNC Symbol;Acc:HGNC:1713]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
codanin 1
Macaque
codanin 1
Mouse
Rat
Dog
codanin 1 [Source:HGNC Symbol;Acc:HGNC:1713]
Publication Statistics
PubMed Score 174.73
PubMed score by year
PubTator Score 136.71
PubTator score by year
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Related Publications
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PMID
Year
Title