CD300LB
CMRF35-like molecule 7
Protein Summary
Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008]
- ENST00000392621
- ENSP00000376397
- ENSG00000178789
- CD300B
- CLM7
- CMRF35A2
- IREM3
- LMIR5
- TREM5
- CLM7
- CLM-7
- IREM3
- TREM5
- CD300b
- IREM-3
- TREM-5
- CMRF35-A2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
tissue sample | 0.64 | ||
cell type or tissue | 0.58 | ||
protein domain | 0.58 | ||
gene perturbation | 0.5 | ||
cell line | 0.49 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.98 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 99 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.98 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 99 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0