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Tbio
CD248
Endosialin

Protein Summary
Description
May play a role in tumor angiogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000311330
  • ENSP00000308117
  • ENSG00000174807

Symbol
  • CD164L1
  • TEM1
  • TEM1
  • CD164L1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
gene perturbation
0.84
cellular component
0.66
tissue
0.61
tissue sample
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1648.8   (req: < 5)
Gene RIFs: 27   (req: <= 3)
Antibodies: 332   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1648.8   (req: >= 5)
Gene RIFs: 27   (req: > 3)
Antibodies: 332   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (52)
RASD2
Tbio
Family:  Enzyme
Novelty:  0.00490468
Score:  0.92
Data Source:  STRINGDB
OXA1L
Tbio
Novelty:  0.00235517
Score:  0.869
Data Source:  STRINGDB
UBAC1
Tbio
Novelty:  0.00122518
Score:  0.86
Data Source:  STRINGDB
PLXDC1
Tbio
Novelty:  0.01025354
Score:  0.848
Data Source:  STRINGDB
IPO5
Tbio
Novelty:  0.00452607
Score:  0.78
Data Source:  STRINGDB
SUMF2
Tbio
Family:  Enzyme
Novelty:  0.07551737
Score:  0.731
Data Source:  STRINGDB
PDGFRB
Tclin
Family:  Kinase
Novelty:  0.00074896
Score:  0.715
Data Source:  STRINGDB
COL1A1
Tbio
Novelty:  0.00063584
Score:  0.689
Data Source:  STRINGDB
COL1A2
Tbio
Novelty:  0.00048334
Score:  0.632
Data Source:  STRINGDB
ADGRA2
Tbio
Family:  GPCR
Novelty:  0.02854335
Score:  0.631
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (14)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
2
2
3
78.7
insomnia measurement
1
2
0
1
67.5
self reported educational attainment
3
2
3
67.4
BMI-adjusted waist circumference
1
2
2
64.9
BMI-adjusted hip circumference
2
1
2
56.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
3
78.7
insomnia measurement
0
1
67.5
self reported educational attainment
3
67.4
BMI-adjusted waist circumference
2
64.9
BMI-adjusted hip circumference
2
56.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
CD248 molecule
VGNC:6480
466674
Macaque
CD248 molecule
714375
Mouse
MGI:1917695
70445
Rat
RGD:11367424
108348067
Dog
CD248 molecule
VGNC:51859
483712
Species
Name
OMA
EggNOG
Inparanoid
Chimp
CD248 molecule
Macaque
CD248 molecule
Mouse
Rat
Dog
CD248 molecule
Publication Statistics
PubMed Score 1648.80
PubMed score by year
PubTator Score 302.72
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title