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Tbio
CCSER1
Serine-rich coiled-coil domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000432775
  • ENSP00000389283
  • ENSG00000184305
  • ENST00000509176
  • ENSP00000425040

Symbol
  • FAM190A
  • KIAA1680
  • FAM190A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
microRNA
0.82
phenotype
0.77
histone modification site profile
0.67
cell line
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.53   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.53   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
NDEL1
Tbio
Novelty:  0.01241819
p_int:  1
Score:  0.617
Data Source:  BioPlex,STRINGDB
SMYD2
Tchem
Family:  Epigenetic
Novelty:  0.0192516
p_int:  0.999996286
p_ni:  9.64e-7
p_wrong:  0.000002751
Score:  0.347
Data Source:  BioPlex,STRINGDB
NDE1
Tbio
Novelty:  0.00567438
p_int:  0.999659694
p_ni:  0.000340306
Score:  0.816
Data Source:  BioPlex,STRINGDB
MAPRE1
Tbio
Novelty:  0.01267772
Score:  0.808
Data Source:  STRINGDB
FAR1
Tbio
Family:  Enzyme
Novelty:  0.01153818
Score:  0.612
Data Source:  STRINGDB
DUSP10
Tbio
Family:  Enzyme
Novelty:  0.01911065
Score:  0.573
Data Source:  STRINGDB
KCNIP4
Tbio
Family:  IC
Novelty:  0.00973829
Score:  0.562
Data Source:  STRINGDB
DACH1
Tbio
Novelty:  0.00986576
Score:  0.558
Data Source:  STRINGDB
AGBL4
Tbio
Family:  Enzyme
Novelty:  0.06139701
Score:  0.543
Data Source:  STRINGDB
WDR62
Tbio
Novelty:  0.02611137
Score:  0.543
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
1
1
1
65.3
self reported educational attainment
2
3
3
55.1
age at first sexual intercourse measurement
1
1
1
37.6
high density lipoprotein cholesterol measurement
1
1
1
31.4
mathematical ability
1
1
1
26.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
1
65.3
self reported educational attainment
3
55.1
age at first sexual intercourse measurement
1
37.6
high density lipoprotein cholesterol measurement
1
31.4
mathematical ability
1
26.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3045354
232035
Rat
RGD:1565731
500153
Cow
coiled-coil serine rich protein 1
VGNC:26993
616908
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Cow
coiled-coil serine rich protein 1
Publication Statistics
PubMed Score 8.53
PubMed score by year
PubTator Score 4.29
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title