You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
CCNYL1
Cyclin-Y-like protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295414
  • ENSP00000295414
  • ENSG00000163249
  • ENST00000339882
  • ENSP00000342344
  • ENST00000392209
  • ENSP00000376045
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
ligand (protein) perturbation
0.83
histone modification site profile
0.76
kinase perturbation
0.76
transcription factor perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.97   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.97   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (65)
CCNY
Tbio
Novelty:  0.01400663
p_int:  0.999996811
p_ni:  0.000003188
p_wrong:  1e-9
Score:  0.717
Data Source:  BioPlex,STRINGDB
CDK16
Tchem
Family:  Kinase
Novelty:  0.02579684
p_int:  0.99998541
p_ni:  0.00001459
Score:  0.931
Data Source:  BioPlex,STRINGDB
GJB7
Tbio
Novelty:  0.12555147
p_int:  0.999804738
p_ni:  0.00019526
p_wrong:  2e-9
Data Source:  BioPlex
S100A7A
Tbio
Novelty:  0.06518939
p_int:  0.999798662
p_ni:  0.000116941
p_wrong:  0.000084396
Score:  0.183
Data Source:  BioPlex,STRINGDB
TMEM185A
Tdark
Novelty:  0.0262898
p_int:  0.999743191
p_ni:  0.000256808
Data Source:  BioPlex
IVL
Tbio
Novelty:  0.00147892
p_int:  0.999717336
p_ni:  0.000282664
Data Source:  BioPlex
TREX2
Tbio
Family:  Enzyme
Novelty:  0.27214255
p_int:  0.999638158
p_ni:  0.000225446
p_wrong:  0.000136395
Score:  0.201
Data Source:  BioPlex,STRINGDB
HOXB5
Tbio
Family:  TF
Novelty:  0.01119871
p_int:  0.999422328
p_ni:  0.00057742
p_wrong:  2.52e-7
Data Source:  BioPlex
DUSP22
Tbio
Family:  Enzyme
Novelty:  0.01579003
p_int:  0.999237945
p_ni:  0.000761948
p_wrong:  1.07e-7
Score:  0.21
Data Source:  BioPlex,STRINGDB
CIR1
Tdark
Novelty:  0.31735301
p_int:  0.998634212
p_ni:  0.001365433
p_wrong:  3.55e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
1
1
1
47.7
hematocrit
2
1
2
39.6
high density lipoprotein cholesterol measurement
1
1
1
8.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
1
47.7
hematocrit
2
39.6
high density lipoprotein cholesterol measurement
1
8.4
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cyclin Y like 1
VGNC:126
737399
Mouse
MGI:2138614
227210
Rat
RGD:1310683
316452
Dog
cyclin Y like 1
488492
Horse
cyclin Y like 1
VGNC:51444
100069061
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cyclin Y like 1
Mouse
Rat
Dog
cyclin Y like 1
Horse
cyclin Y like 1
Publication Statistics
PubMed Score 2.97
PubMed score by year
PubTator Score 0.50
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title