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Tchem
CCNB1
G2/mitotic-specific cyclin-B1

Protein Summary
Description
Essential for the control of the cell cycle at the G2/M (mitosis) transition. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary for proper control of the G2/M transition phase of the cell cycle. [provided by RefSeq, Aug 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000256442
  • ENSP00000256442
  • ENSG00000134057
  • ENST00000505500
  • ENSP00000424588

Symbol
  • CCNB
  • CCNB
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
1
chemical
1
transcription factor perturbation
0.99
interacting protein
0.96
virus perturbation
0.85


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1742.44   (req: < 5)
Gene RIFs: 194   (req: <= 3)
Antibodies: 1709   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1742.44   (req: >= 5)
Gene RIFs: 194   (req: > 3)
Antibodies: 1709   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 46
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0