CCL20
C-C motif chemokine 20
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.99 | ||
virus perturbation | 0.99 | ||
biological term | 0.92 | ||
small molecule perturbation | 0.81 | ||
biological process | 0.73 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Chemokine receptors bind chemokines | ||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Chemokine receptors bind chemokines | ||||
Class A/1 (Rhodopsin-like receptors) | ||||
Cytokine Signaling in Immune system | ||||
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
childhood onset asthma | 2 | 2 | 0 | 1.1 | 83.4 | ||||
4 | 3 | 0 | 1 | 66.8 | |||||
3 | 2 | 2 | 1 | 57.7 | |||||
age at onset | 2 | 1 | 1 | 1.1 | 56.8 | ||||
3 | 3 | 0 | 1 | 56.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
childhood onset asthma | 0 | 1.1 | 83.4 | ||||
0 | 1 | 66.8 | |||||
2 | 1 | 57.7 | |||||
age at onset | 1 | 1.1 | 56.8 | ||||
0 | 1 | 56.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | C-C motif chemokine ligand 20 | VGNC:125 | 459991 | |||||
Macaque | C-C motif chemokine ligand 20 | 574182 | ||||||
Mouse | MGI:1329031 | 20297 | ||||||
Rat | RGD:3646 | 29538 | ||||||
Dog | C-C motif chemokine ligand 20 | VGNC:38884 | 448790 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | C-C motif chemokine ligand 20 | |||||
Macaque | C-C motif chemokine ligand 20 | |||||
Mouse | ||||||
Rat | ||||||
Dog | C-C motif chemokine ligand 20 | |||||
PMID | Year | Title |
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