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Tdark
CCDC97
Coiled-coil domain-containing protein 97

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000269967
  • ENSP00000269967
  • ENSG00000142039
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.85
histone modification site profile
0.75
microRNA
0.61
transcription factor perturbation
0.61
cellular component
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.53   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.53   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (66)
PAXIP1
Tbio
Novelty:  0.01728724
p_int:  0.999999809
p_ni:  1.9e-7
p_wrong:  1e-9
Score:  0.19
Data Source:  BioPlex,STRINGDB
TTC33
Tdark
Novelty:  0.31237949
p_int:  0.999998824
p_ni:  0.000001176
Score:  0.663
Data Source:  BioPlex,STRINGDB
PHF5A
Tbio
Family:  Epigenetic
Novelty:  0.02989472
p_int:  0.999996428
p_ni:  0.000003571
p_wrong:  1e-9
Score:  0.54
Data Source:  BioPlex,STRINGDB
SF3A2
Tbio
Novelty:  0.03658692
p_int:  0.99999285
p_ni:  0.000005812
p_wrong:  0.000001338
Score:  0.623
Data Source:  BioPlex,STRINGDB
SF3A3
Tbio
Novelty:  0.03815499
p_int:  0.999976154
p_ni:  0.000023846
Score:  0.534
Data Source:  BioPlex,STRINGDB
SF3A1
Tbio
Novelty:  0.03405702
p_int:  0.999886996
p_ni:  0.000113004
Score:  0.803
Data Source:  BioPlex,STRINGDB
SF3B1
Tbio
Novelty:  0.0128965
p_int:  0.99988672
p_ni:  0.00011328
Score:  0.983
Data Source:  BioPlex,STRINGDB
CIZ1
Tbio
Novelty:  0.03730538
p_int:  0.99987005
p_ni:  0.00012995
Score:  0.173
Data Source:  BioPlex,STRINGDB
ATF1
Tchem
Family:  TF
Novelty:  0.01450941
p_int:  0.999653255
p_ni:  0.000290004
p_wrong:  0.000056741
Data Source:  BioPlex
SF3B4
Tbio
Novelty:  0.0197008
p_int:  0.9987792
p_ni:  0.0012208
Score:  0.158
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (24)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
8
9
6
1.1
94.6
heel bone mineral density
3
4
8
93.3
serum gamma-glutamyl transferase measurement
2
2
2
92.6
balding measurement
1
2
2
90.8
body height
2
2
2
85.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
6
1.1
94.6
heel bone mineral density
8
93.3
serum gamma-glutamyl transferase measurement
2
92.6
balding measurement
2
90.8
body height
2
85.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 97
VGNC:10958
456059
Macaque
coiled-coil domain containing 97
706342
Mouse
MGI:1196455
52132
Rat
RGD:1309393
292724
Dog
coiled-coil domain containing 97
VGNC:38876
484489
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 97
Macaque
coiled-coil domain containing 97
Mouse
Rat
Dog
coiled-coil domain containing 97
Publication Statistics
PubMed Score 0.53
PubMed score by year
PubTator Score 0.14
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title