Tbio CCDC93 Coiled-coil domain-containing protein 93

Protein Summary

Description

Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947).

Uniprot Accession IDs

• Q567U6
• A8K3V7
• Q4LE78
• Q53TJ2
• Q8TBX5
• Q9H6R5
• Q9NV15

Gene Name

• CCDC93

Ensembl ID

• ENST00000376300
• ENSP00000365477
• ENSG00000125633

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.88
virus perturbation	0.88
histone modification site profile	0.8
microRNA	0.65
disease perturbation	0.62

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.24   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 203   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.24   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 203   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0