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Tdark
CCDC84
Coiled-coil domain-containing protein 84

Protein Summary
Description
This gene encodes a protein thought to contain a coiled coil motif. No function has been determined for the encoded protein. A pseudogene of this gene is located on chromosome 20. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334418
  • ENSP00000334767
  • ENSG00000186166
  • ENST00000625528
  • ENSP00000487197
  • ENSG00000280975

Symbol
  • DLNB14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.93
cell type or tissue
0.81
transcription factor binding site profile
0.69
tissue sample
0.6
tissue
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
TXNL4B
Tbio
Novelty:  0.00695407
p_int:  0.999998492
p_ni:  1.6e-8
p_wrong:  0.000001493
Score:  0.54
Data Source:  BioPlex,STRINGDB
PRPF3
Tbio
Novelty:  0.01600014
p_int:  0.999991025
p_ni:  0.000008975
Score:  0.692
Data Source:  BioPlex,STRINGDB
SNRPGP15
Tdark
p_int:  0.999959377
p_ni:  0.000001462
p_wrong:  0.000039161
Data Source:  BioPlex
TUT1
Tbio
Family:  Enzyme
Novelty:  0.01436913
p_int:  0.999007089
p_ni:  0.000992905
p_wrong:  6e-9
Score:  0.874
Data Source:  BioPlex,STRINGDB
SNRPE
Tbio
Novelty:  0.02033423
p_int:  0.99750524
p_ni:  0.000014511
p_wrong:  0.002480249
Score:  0.534
Data Source:  BioPlex,STRINGDB
WDR83
Tbio
Novelty:  0.11602568
p_int:  0.987147941
p_ni:  0.012852059
Score:  0.198
Data Source:  BioPlex,STRINGDB
GINS1
Tbio
Novelty:  0.08722396
p_int:  0.848772677
p_ni:  0.151205342
p_wrong:  0.000021981
Score:  0.228
Data Source:  BioPlex,STRINGDB
SART3
Tbio
Novelty:  0.02353492
p_int:  0.83619957
p_ni:  0.16380043
Score:  0.534
Data Source:  BioPlex,STRINGDB
Q9H496
Tbio
Novelty:  0.08912351
Score:  0.732
Data Source:  STRINGDB
Q8NFQ8
Tbio
Novelty:  0.08912351
Score:  0.732
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (62)
Items per page:
1 – 5 of 62
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
21
4
21
89.4
high density lipoprotein cholesterol measurement
21
4
21
89.4
body mass index
4
4
4
84
body mass index
4
4
4
84
serum albumin measurement
2
2
2
78.9
Items per page:
1 – 5 of 62
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
21
89.4
high density lipoprotein cholesterol measurement
21
89.4
body mass index
4
84
body mass index
4
84
serum albumin measurement
2
78.9
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2685960
382073
Rat
RGD:1597440
689046
Dog
coiled-coil domain containing 84
VGNC:38862
610660
Horse
coiled-coil domain containing 84
VGNC:16181
100071299
Cow
coiled-coil domain containing 84
VGNC:26922
512413
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
coiled-coil domain containing 84
Horse
coiled-coil domain containing 84
Cow
coiled-coil domain containing 84
Publication Statistics
PubMed Score 1.47
PubMed score by year
PubTator Score 0.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title