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Tdark
CCDC83
Coiled-coil domain-containing protein 83

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000280245
  • ENSP00000280245
  • ENSG00000150676
  • ENST00000342404
  • ENSP00000344512

Symbol
  • HSD9
  • CT148
  • KP-CoT-23
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
cell type or tissue
0.67
transcription factor binding site profile
0.66
cell line
0.61
virus perturbation
0.5


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.53   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 137   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.53   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 137   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
MCC
Tbio
Novelty:  0.10374312
p_int:  0.999950455
p_ni:  0.000049154
p_wrong:  3.91e-7
Score:  0.214
Data Source:  BioPlex,STRINGDB
RBM12
Tbio
Novelty:  0.10430477
p_int:  0.990827959
p_ni:  0.009172041
Data Source:  BioPlex
CHMP2A
Tbio
Novelty:  0.00169253
p_int:  0.848900325
p_ni:  0.133749306
p_wrong:  0.017350369
Score:  0.188
Data Source:  BioPlex,STRINGDB
KLC1
Tbio
Novelty:  0.00653484
p_int:  0.841593135
p_ni:  0.158406865
Score:  0.177
Data Source:  BioPlex,STRINGDB
PPID
Tchem
Family:  Enzyme
Novelty:  0.01068886
p_int:  0.835529693
p_ni:  0.012030503
p_wrong:  0.152439805
Score:  0.187
Data Source:  BioPlex,STRINGDB
TTC33
Tdark
Novelty:  0.31237949
p_int:  0.830684576
p_ni:  0.164155758
p_wrong:  0.005159666
Score:  0.243
Data Source:  BioPlex,STRINGDB
ASPM
Tbio
Novelty:  0.00599688
p_int:  0.788726627
p_ni:  0.211273373
Data Source:  BioPlex
ZNF469
Tbio
Family:  TF
Novelty:  0.03776751
Score:  0.647
Data Source:  STRINGDB
HEPACAM2
Tbio
Novelty:  0.19192547
Score:  0.598
Data Source:  STRINGDB
FTSJ1
Tbio
Family:  Enzyme
Novelty:  0.01511808
Score:  0.496
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum albumin measurement
1
1
1
30.2
1
1
0
1.3
21.5
self reported educational attainment
1
1
1
3.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum albumin measurement
1
30.2
0
1.3
21.5
self reported educational attainment
1
3.1
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 83
VGNC:3166
749077
Macaque
coiled-coil domain containing 83
703306
Mouse
MGI:1918255
75338
Dog
coiled-coil domain containing 83
VGNC:38861
476781
Horse
coiled-coil domain containing 83
VGNC:16180
100050777
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 83
Macaque
coiled-coil domain containing 83
Mouse
Dog
coiled-coil domain containing 83
Horse
coiled-coil domain containing 83
Publication Statistics
PubMed Score 3.53
PubMed score by year
PubTator Score 3.00
PubTator score by year
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Related Publications
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PMID
Year
Title