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Tdark
CCDC74B
Coiled-coil domain-containing protein 74B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000310463
  • ENSP00000308873
  • ENSG00000152076
  • ENST00000409943
  • ENSP00000386294
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.59
virus perturbation
0.59
cellular component
0.52
cell line
0.46
tissue
0.45


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.55   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.55   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
CCDC74A
Tdark
Novelty:  1.52601156
p_int:  1
Score:  0.213
Data Source:  BioPlex,STRINGDB
THNSL1
Tdark
Family:  Enzyme
Novelty:  1.98275016
p_int:  0.999956075
p_ni:  0.000043925
Data Source:  BioPlex
PSMD7
Tbio
Family:  Enzyme
Novelty:  0.03090292
p_int:  0.998019574
p_ni:  0.001980426
Score:  0.815
Data Source:  BioPlex,STRINGDB
PSMD4
Tbio
Family:  Enzyme
Novelty:  0.00614538
p_int:  0.99735411
p_ni:  0.00264589
Score:  0.816
Data Source:  BioPlex,STRINGDB
PSMD12
Tbio
Family:  Enzyme
Novelty:  0.03178037
p_int:  0.993469727
p_ni:  0.006530273
Score:  0.827
Data Source:  BioPlex,STRINGDB
PSMD8
Tbio
Family:  Enzyme
Novelty:  0.03053455
p_int:  0.993167642
p_ni:  0.006832358
Score:  0.682
Data Source:  BioPlex,STRINGDB
PSMC4
Tchem
Family:  Enzyme
Novelty:  0.01717597
p_int:  0.992733968
p_ni:  0.007266032
Score:  0.817
Data Source:  BioPlex,STRINGDB
PSMD1
Tbio
Family:  Enzyme
Novelty:  0.02168311
p_int:  0.99269873
p_ni:  0.00730127
Score:  0.828
Data Source:  BioPlex,STRINGDB
PSMD11
Tbio
Family:  Enzyme
Novelty:  0.02148951
p_int:  0.992124287
p_ni:  0.007875713
Score:  0.768
Data Source:  BioPlex,STRINGDB
PSMC6
Tbio
Family:  Enzyme
Novelty:  0.00168013
p_int:  0.990811116
p_ni:  0.009188884
Score:  0.811
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 0.55
PubMed score by year
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Related Publications
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PMID
Year
Title