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Tdark
CCDC74A
Coiled-coil domain-containing protein 74A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295171
  • ENSP00000295171
  • ENSG00000163040
  • ENST00000409856
  • ENSP00000387009
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.73
cell line
0.56
histone modification site profile
0.55
cellular component
0.52
cell type or tissue
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
CCDC74B
Tdark
Novelty:  1.7435743
p_int:  1
Score:  0.213
Data Source:  BioPlex,STRINGDB
MAN2B2
Tbio
Family:  Enzyme
Novelty:  0.11499103
p_int:  0.999999944
p_ni:  5.6e-8
Data Source:  BioPlex
CEP76
Tdark
Novelty:  0.3880387
p_int:  0.999992868
p_ni:  0.000007132
Data Source:  BioPlex
LIN54
Tbio
Novelty:  0.06173892
p_int:  0.999957239
p_ni:  0.000042761
Data Source:  BioPlex
THNSL1
Tdark
Family:  Enzyme
Novelty:  1.98275016
p_int:  0.999927817
p_ni:  0.000072183
Data Source:  BioPlex
RGPD8
Tdark
Novelty:  0.12397737
p_int:  0.999695023
p_ni:  0.000304977
Data Source:  BioPlex
LIN9
Tbio
Novelty:  0.01112853
p_int:  0.989531598
p_ni:  0.010431219
p_wrong:  0.000037183
Data Source:  BioPlex
UCHL5
Tbio
Family:  Enzyme
Novelty:  0.01486265
p_int:  0.985138717
p_ni:  0.014861283
Data Source:  BioPlex
ADRM1
Tbio
Novelty:  0.01545209
p_int:  0.980821465
p_ni:  0.019178535
Data Source:  BioPlex
BTBD1
Tbio
Novelty:  0.19772296
p_int:  0.975090488
p_ni:  0.024909348
p_wrong:  1.64e-7
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1919565
72315
Dog
coiled-coil domain-containing protein 74B
608483
Horse
coiled-coil domain-containing protein 74B
100052145
Cow
coiled-coil domain containing 74B
789735
Pig
coiled-coil domain containing 74B
100625918
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
coiled-coil domain-containing protein 74B
Horse
coiled-coil domain-containing protein 74B
Cow
coiled-coil domain containing 74B
Pig
coiled-coil domain containing 74B
Publication Statistics
PubMed Score 0.85
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title